|
631
|
| 3354 |
Status epilepticus
|
|
affects_phosphorylation of
|
GRIN2B
|
in lithium/pilocarpine model
|
| 3356 |
SRC
|
|
affects_phosphorylation of
|
GRIN2B
|
in lithium/pilocarpine model
|
|
15748156
|
Status epilepticus
|
|
1,044
|
| 123555 |
GRIN2B
|
|
affects_activity of
|
Schizophrenia
|
|
|
15841096
|
Schizophrenia
|
|
1,046
|
| 6550 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2B
|
|
|
8139656
|
Neurological
Schizophrenia
|
|
1,048
|
| 6555 |
GRIN2A
|
|
interacts (colocalizes) with
|
GRIN2B
|
|
|
12191494
|
Neurological
Schizophrenia
|
|
1,254
|
| 8495 |
SRC
|
|
affects_phosphorylation of
|
GRIN2B
|
|
| 8502 |
Ifenprodil
|
|
decreases_activity of
|
GRIN2B
|
|
|
18952671
|
Epilepsy, temporal lobe
|
|
1,870
|
| 14218 |
TTBK1-Tg mouse
|
|
decreases_quantity of
|
GRIN2B
|
|
|
19118186
|
Alzheimer disease
|
|
1,899
|
| 14509 |
high-fat diet
|
|
affects_expression of
|
GRIN2B
|
in hypothalamus
|
|
16002529
|
Diabetes mellitus, type II
Insulin resistance
|
|
3,870
|
| 39540 |
Alzheimer disease
|
|
decreases_expression of
|
GRIN2B
|
in hippocampus and entorhinal cortex from AD brains
|
| 81322 |
FYN
|
|
increases_phosphorylation of
|
GRIN2B
|
|
|
23162743
|
Alzheimer disease
Huntington disease
|
|
4,711
|
| 46710 |
GRIN2B
|
|
affects_activity of
|
regulation of synaptic plasticity
|
in VTA DA neurons; if synaptic plasticity is induced by cocaine;
|
| 46720 |
GRIN2B
|
|
increases_activity of
|
long-term synaptic potentiation
|
in CA1 hippocampal neurons; when low frequency stimulation (LFS) paired with depolarization was used;
|
|
19524640
|
Neurological
|
|
4,964
|
| 49492 |
DRD2
|
|
interacts (colocalizes) with
|
GRIN2B
|
|
| 49493 |
GRIN2B
|
|
is_part_of
|
NMDA receptor complex
|
|
| 49494 |
DRD2
|
|
decreases_phosphorylation of
|
GRIN2B
|
stimulation of D2 reduces phosphorylation of NR2B
|
|
23253944
|
Neurological
Schizophrenia
|
|
5,025
|
| 49590 |
GRM5
|
|
affects_quantity of
|
GRIN2B
|
|
| 49592 |
GRIN2B
|
|
affects_activity of
|
NMDA receptor complex
|
|
|
21521618
|
Schizophrenia
|
|
5,037
|
| 49697 |
GRM5
|
|
affects_quantity of
|
GRIN2B
|
in hippocampus
|
|
24024939
|
Schizophrenia
|
|
5,040
|
| 49710 |
GRIN2B
|
|
interacts (colocalizes) with
|
RASGRF1
|
as shown in HEK293T cells and
in rat brain microsomes
|
| 65978 |
GRIN2B
|
|
increases_activity of
|
ERK1 and ERK2 cascade
|
|
|
14622581
|
Neurological
|
|
5,059
|
| 49762 |
PRKCA
|
|
increases_phosphorylation of
|
GRIN2B
|
|
|
16919684
|
Neurological
|
|
5,060
|
| 49773 |
PRKCA
|
|
increases_phosphorylation of
|
GRIN2B
|
in hippocampal CA1
|
|
11158244
|
Neurological
|
|
5,103
|
| 50142 |
PTPN5
|
|
decreases_phosphorylation of
|
GRIN2B
|
|
|
22781170
|
Schizophrenia
|
|
6,632
|
| 63384 |
Lithium
|
|
decreases_phosphorylation of
|
GRIN2B
|
at Tyr1472
|
| 63385 |
GRIN2B
|
|
increases_activity of
|
calcium ion import
|
|
| 63387 |
GRIN2B
|
|
is_part_of
|
NMDA receptor complex
|
|
|
11841566
|
Neurological
|
|
6,752
|
| 65720 |
RASGRF1
|
|
interacts (colocalizes) with
|
GRIN2B
|
|
|
21111786
|
Neurological
|
|
6,755
|
| 65705 |
DLG4
|
|
interacts (colocalizes) with
|
GRIN2B
|
as shown in coimmunoprecipitates from rat forebrain.
|
|
10488080
|
Neurological
|
|
6,759
|
| 65713 |
DLG4
|
|
interacts (colocalizes) with
|
GRIN2B
|
|
|
18367167
|
Neurological
|
|
9,001
|
| 94377 |
APOE (isoform E4)
|
|
decreases_phosphorylation of
|
GRIN2B
|
Reelin-induced GluN2A and GluN2B tyrosine phosphorylation is decreased
|
| 94380 |
APOE (isoform E4)
|
|
decreases_quantity of
|
GRIN2B
|
in acutely Reelin
stimulated primary neurons; the cell-surface levels
|
|
20547867
|
Alzheimer disease
|
|
9,047
|
| 94567 |
APOE (isoform E4)
|
|
decreases_expression of
|
GRIN2B
|
in prefrontal cortex
|
|
27103636
|
Alzheimer disease
|
|
9,151
|
| 97951 |
GF mouse
|
|
decreases_expression of
|
GRIN2B
|
|
|
27566465
|
Alzheimer disease
Gastrointestinal
Metabolic
|
|
11,097
|
| 112578 |
GRIN2B
|
|
affects_activity of
|
Cerebral visual impairment
|
|
|
26350515
|
Ophtalmological
Intellectual disability
|
|
11,572
|
| 115351 |
GRIN2B
|
|
affects_activity of
|
Epileptic encephalopathy, early infantile, 27
|
|
| 115356 |
GRIN2B
|
|
increases_activity of
|
synaptic transmission, glutamatergic
|
|
| 115358 |
GRIN2B
|
|
affects_activity of
|
intellectual disability
|
|
| 115360 |
GRIN2B
|
|
affects_activity of
|
Autism
|
|
| 115361 |
GRIN2B
|
|
affects_activity of
|
developmental delay
|
|
| 115362 |
GRIN2B
|
|
affects_activity of
|
seizures
|
|
|
28377535
|
Neurodevelopmental disease
|
|
11,573
|
| 115363 |
GRIN2B
|
|
affects_activity of
|
Mental retardation, autosomal dominant 6
|
|
|
20890276
|
Mental retardation
|
|
11,574
|
| 115368 |
GRIN2B
|
|
increases_activity of
|
dendrite development
|
|
| 115413 |
GRIN2B
|
|
increases_activity of
|
calcium ion transport
|
|
|
31548203
|
Neurological
|
|
11,576
|
| 115418 |
response to hypoxia
|
|
decreases_expression of
|
GRIN2B
|
in hippocampus
|
|
26656067
|
Neurological
Developmental
|
|
11,578
|
| 115427 |
aging
|
|
decreases_expression of
|
GRIN2B
|
in cerebral cortex and specific hippocampal regions
|
| 115428 |
GRIN2B
|
|
increases_activity of
|
learning or memory
|
during aging
|
|
25206584
|
Neurological
Developmental
|
|
12,889
|
| 123557 |
GRIN2B
|
|
is_part_of
|
NMDA receptor complex
|
|
| 123558 |
GRIN2B
|
|
affects_activity of
|
Alzheimer disease
|
|
|
18983893
|
Neurodegenerative disorder
|
CIDeRplus