526
|
2620 |
Polyinosinic:polycytidylic acid
|
|
increases_expression of
|
GRIN2A
|
|
|
19660546
|
Epilepsy
|
631
|
3353 |
Status epilepticus
|
|
affects_phosphorylation of
|
GRIN2A
|
in lithium/pilocarpine model
|
3355 |
SRC
|
|
affects_phosphorylation of
|
GRIN2A
|
in lithium/pilocarpine model
|
|
15748156
|
Status epilepticus
|
1,046
|
6548 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2A
|
|
|
8139656
|
Neurological
Schizophrenia
|
1,048
|
6555 |
GRIN2A
|
|
interacts (colocalizes) with
|
GRIN2B
|
|
|
12191494
|
Neurological
Schizophrenia
|
3,870
|
39539 |
Alzheimer disease
|
|
decreases_expression of
|
GRIN2A
|
in hippocampus and entorhinal cortex from AD brains
|
81321 |
FYN
|
|
increases_phosphorylation of
|
GRIN2A
|
|
|
23162743
|
Alzheimer disease
Huntington disease
|
4,711
|
46683 |
NVP-AAM077
|
|
decreases_activity of
|
GRIN2A
|
in VTA neurons; and blocks cocaine-induced increase in the AMPAR/NMDAR currents ratio;
|
46684 |
GRIN2A
|
|
affects_activity of
|
locomotory behavior
|
caused by repeated cocaine injections
|
46709 |
GRIN2A
|
|
affects_activity of
|
regulation of synaptic plasticity
|
in VTA DA neurons; if synaptic plasticity is induced by cocaine;
|
46719 |
GRIN2A
|
|
increases_activity of
|
long-term synaptic potentiation
|
in CA1 hippocampal neurons; when low frequency stimulation (LFS) paired with depolarization was used;
|
49588 |
GRIN2A
|
|
is_part_of
|
NMDA receptor complex
|
|
|
19524640
|
Neurological
|
4,891
|
48317 |
mir-137
|
|
affects_expression of
|
GRIN2A
|
|
|
23637704
|
Schizophrenia
|
5,021
|
49581 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2A
|
|
|
11279200
|
Neurological
|
5,023
|
49585 |
GRIN2A
|
|
is_part_of
|
NMDA receptor complex
|
|
|
10480938
|
Neurological
|
5,024
|
53420 |
Glutamate
|
|
interacts (colocalizes) with
|
GRIN2A
|
|
|
16281028
|
Neurological
|
5,025
|
49589 |
GRM5
|
|
affects_quantity of
|
GRIN2A
|
|
49591 |
GRIN2A
|
|
affects_activity of
|
NMDA receptor complex
|
|
|
21521618
|
Schizophrenia
|
5,037
|
49696 |
GRM5
|
|
affects_quantity of
|
GRIN2A
|
in hippocampus
|
49698 |
GRIN2A
|
|
affects_activity of
|
cerebral cortex GABAergic interneuron development
|
|
49699 |
GRIN2A
|
|
affects_activity of
|
interneuron
|
|
|
24024939
|
Schizophrenia
|
5,039
|
49709 |
GRIN2A
|
|
interacts (colocalizes) with
|
RASGRF2
|
in hippocampus
|
|
16467520
|
Neurological
|
5,056
|
49751 |
DLG4
|
|
interacts (colocalizes) with
|
GRIN2A
|
in telencephalon
|
49752 |
FYN
|
|
increases_phosphorylation of
|
GRIN2A
|
in telencephalon
|
|
9892651
|
Neurological
|
5,059
|
49761 |
PRKCA
|
|
increases_phosphorylation of
|
GRIN2A
|
|
|
16919684
|
Neurological
|
5,060
|
49763 |
PRKCA
|
|
increases_phosphorylation of
|
GRIN2A
|
in hippocampal CA1
|
|
11158244
|
Neurological
|
5,193
|
50793 |
D-Serine
|
|
decreases_activity of
|
GRIN2A
|
in hippocampus
|
|
25042179
|
Neurological
|
6,752
|
65721 |
RASGRF1
|
NOT |
interacts (colocalizes) with
|
GRIN2A
|
|
|
21111786
|
Neurological
|
6,759
|
65712 |
DLG4
|
|
interacts (colocalizes) with
|
GRIN2A
|
|
|
18367167
|
Neurological
|
9,001
|
94369 |
APOE (isoform E4)
|
|
decreases_phosphorylation of
|
GRIN2A
|
Reelin-induced GluN2A and GluN2B tyrosine phosphorylation is decreased
|
|
20547867
|
Alzheimer disease
|
10,525
|
108645 |
GRIN2A
|
|
affects_activity of
|
Autism
|
|
|
21358714
|
Autism
|
11,532
|
115145 |
RNF10
|
|
interacts (colocalizes) with
|
GRIN2A
|
in primary rat hippocampal cells
|
|
26977767
|
Neurodevelopmental disease
|
11,576
|
115424 |
response to hypoxia
|
|
decreases_expression of
|
GRIN2A
|
in hippocampus
|
|
26656067
|
Neurological
Developmental
|
14,128
|
133503 |
MAP2
|
|
interacts (colocalizes) with
|
GRIN2A
|
in normoxic adult rat hippocampal slice
|
|
12834896
|
Neurological
Alzheimer disease
|
16,106
|
155361 |
GRIN2A-mut
|
|
affects_activity of
|
GRIN2A
|
in targeted mouse
|
155375 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2A
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155383 |
GRIN2A
|
|
interacts (colocalizes) with
|
GRIN2B
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155384 |
GRIN2A
|
|
interacts (colocalizes) with
|
DLG4
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155385 |
GRIN2A
|
|
interacts (colocalizes) with
|
DLG2
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155386 |
GRIN2A
|
|
interacts (colocalizes) with
|
DLG3
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155387 |
GRIN2A
|
|
interacts (colocalizes) with
|
CAMK2B
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155388 |
GRIN2A
|
|
interacts (colocalizes) with
|
PLCG
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155389 |
GRIN2A
|
|
interacts (colocalizes) with
|
Spectrin
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155401 |
GRIN2A
|
|
is_part_of
|
NMDA receptor-associated protein complex (NRC)
|
in mouse brain
|
155518 |
GRIN2A
|
|
is_part_of
|
NMDA receptor complex
|
in mouse brain
|
|
|
Neurological
|
16,114
|
155945 |
GRIN2A
|
|
is_part_of
|
NMDA receptor-associated protein complex (NRC)
|
in mouse brain
|
|
|
Neurological
|
16,133
|
156064 |
aging
|
NOT |
affects_expression of
|
GRIN2A
|
NR2A mRNA levels remained constant, leading to an age-related increase in NR2A/2B transcript ratio.
|
|
|
Neurological
|
16,134
|
156107 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2A
|
|
156110 |
GRIN2A
|
|
affects_activity of
|
NMDA receptor complex (GRIN1, GRIN2A)
|
|
|
|
Neurological
|
16,147
|
156223 |
RASGRF2
|
NOT |
interacts (colocalizes) with
|
GRIN2A
|
|
156228 |
DRD1
|
|
interacts (colocalizes) with
|
GRIN2A
|
in rat hippocampal tissue
|
156241 |
DRD5
|
NOT |
interacts (colocalizes) with
|
GRIN2A
|
in vitro
|
|
|
Neurological
|
16,149
|
156229 |
DRD1
|
|
interacts (colocalizes) with
|
GRIN2A
|
|
156233 |
GRIN2A
|
|
is_part_of
|
DRD1-GRIN2A complex
|
|
|
|
Neurological
|