631
|
3348 |
PRKCG
|
|
increases_phosphorylation of
|
GRIN1
|
after status epilepticus in lithium/pilocarpine model
|
3349 |
PRKCA
|
|
increases_phosphorylation of
|
GRIN1
|
after status epilepticus in lithium/pilocarpine model
|
3350 |
Status epilepticus
|
|
increases_phosphorylation of
|
GRIN1
|
after 1h of pilocarpine administration
|
|
15748156
|
Status epilepticus
|
993
|
6160 |
CIT
|
|
interacts (colocalizes) with
|
GRIN1
|
|
|
10862698
|
Neurological
Schizophrenia
|
1,046
|
6548 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2A
|
|
6550 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2B
|
|
|
8139656
|
Neurological
Schizophrenia
|
1,048
|
6553 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2D
|
|
|
12191494
|
Neurological
Schizophrenia
|
1,384
|
9548 |
NFKB1
|
|
affects_expression of
|
GRIN1
|
|
|
12679240
|
Schizophrenia
|
1,934
|
15059 |
Alzheimer disease
|
|
decreases_expression of
|
GRIN1
|
(the surface expression of NR1 in APPSwe mice compared to wild-type littermates)
|
15075 |
Methyllycaconitine
|
|
increases_quantity of
|
GRIN1
|
|
49369 |
GRIN1
|
|
is_part_of
|
NMDA receptor complex
|
|
|
16025111
|
Alzheimer disease
|
2,445
|
22738 |
Alzheimer disease
|
|
affects_expression of
|
GRIN1
|
in hippocampus, cerebellum, and gyrus frontalis medialis; in stages V-VI of AD
|
|
17361039
|
Alzheimer disease
|
4,178
|
43005 |
Schizophrenia
|
|
increases_expression of
|
GRIN1
|
in dorsolateral prefrontal cortex
|
43006 |
Schizophrenia
|
|
increases_quantity of
|
GRIN1
|
in dorsolateral prefrontal cortex
|
|
2307007
|
Schizophrenia
|
4,205
|
43137 |
Diabetes mellitus, type II
|
|
increases_expression of
|
GRIN1
|
in retina
|
|
18258217
|
Diabetes mellitus, type II
Insulin resistance
Retinopathy, diabetic
|
5,017
|
49552 |
NLGN1
|
|
interacts (colocalizes) with
|
GRIN1
|
|
49553 |
GRIN1
|
|
is_part_of
|
NMDA receptor complex
|
|
|
24497299
|
Neurological
|
5,021
|
49581 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2A
|
|
|
11279200
|
Neurological
|
5,024
|
49586 |
Glycine
|
|
interacts (colocalizes) with
|
GRIN1
|
|
|
16281028
|
Neurological
|
8,644
|
89370 |
Trimethylamine N-oxide
|
|
decreases_quantity of
|
GRIN1
|
in hippocampus; by downregulation of TOR signaling
|
89377 |
GRIN1
|
|
affects_activity of
|
regulation of synaptic plasticity
|
in hippocampus
|
|
29749694
|
Metabolic
|
9,050
|
94748 |
exercise
|
|
decreases_activity of
|
GRIN1
|
in the central nervous system; by reducing the phosphorylation of NR1
|
94750 |
GRIN1
|
|
increases_activity of
|
synaptic transmission, glutamatergic
|
in the central nervous system
|
|
27624384
|
Metabolic
|
11,097
|
112577 |
GRIN1
|
|
affects_activity of
|
Cerebral visual impairment
|
|
|
26350515
|
Ophtalmological
Intellectual disability
|
11,576
|
115422 |
response to hypoxia
|
|
decreases_expression of
|
GRIN1
|
in hippocampus
|
|
26656067
|
Neurological
Developmental
|
16,105
|
155336 |
AKAP9
|
|
interacts (colocalizes) with
|
GRIN1
|
NR1/GRIN1 is the subunit of the NMDA receptor
|
155338 |
GRIN1
|
|
is_part_of
|
AKAP9-GRIN1-PRKAR2A-PRKAR2B complex
|
in rat brain in striatal and cerebellar neurons
|
|
|
Neurological
|
16,106
|
155358 |
GRIN1-mut
|
|
affects_activity of
|
GRIN1
|
in targeted mouse
|
155374 |
GRIN1
|
|
is_part_of
|
NMDA receptor-associated protein complex (NRC)
|
in mouse brain
|
155375 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2A
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155376 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2B
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155377 |
GRIN1
|
|
interacts (colocalizes) with
|
AKAP9
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155378 |
GRIN1
|
|
interacts (colocalizes) with
|
CAMK2B
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155379 |
GRIN1
|
|
interacts (colocalizes) with
|
CALM
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155380 |
GRIN1
|
|
interacts (colocalizes) with
|
ACTN2
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155381 |
GRIN1
|
|
interacts (colocalizes) with
|
Spectrin
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155382 |
GRIN1
|
|
interacts (colocalizes) with
|
TUB
|
in mouse brain; as part of the NMDAR multiprotein complex (NRC)
|
155517 |
GRIN1
|
|
is_part_of
|
NMDA receptor complex
|
in mouse brain
|
|
|
Neurological
|
16,114
|
155947 |
GRIN1
|
|
is_part_of
|
NMDA receptor-associated protein complex (NRC)
|
in mouse brain
|
|
|
Neurological
|
16,133
|
156062 |
aging
|
|
increases_expression of
|
GRIN1
|
in CA4, CA3 and CA2 subfields; Levels of NR1 mRNA were significantly lower in the neonate than all other age groups.
|
|
|
Neurological
|
16,134
|
156107 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2A
|
|
156108 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2B
|
|
156109 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2C
|
|
156114 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN2D
|
|
|
|
Neurological
|
16,147
|
156224 |
DRD1
|
|
interacts (colocalizes) with
|
GRIN1
|
in rat hippocampal tissue
|
156242 |
DRD5
|
NOT |
interacts (colocalizes) with
|
GRIN1
|
in vitro
|
156246 |
DRD2
|
NOT |
interacts (colocalizes) with
|
GRIN1
|
|
|
|
Neurological
|
16,149
|
156226 |
DRD1
|
|
interacts (colocalizes) with
|
GRIN1
|
|
156232 |
GRIN1
|
|
is_part_of
|
DRD1-GRIN1 complex
|
|
|
|
Neurological
|
16,162
|
156307 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN1
|
in mouse and rat; forming homo-oligomeric aggregates
|
156308 |
GRIN1
|
|
interacts (colocalizes) with
|
GRIN3A
|
in mouse and rat
|
156311 |
GRIN1
|
|
interacts (colocalizes) with
|
Glycine
|
|
156318 |
GRIN1
|
|
is_part_of
|
NMDA receptor complex (GRIN1, GRIN3A)
|
in mouse and rat
|
156319 |
GRIN1
|
|
is_part_of
|
NMDA receptor complex (GRIN1, GRIN2A)
|
|
156320 |
GRIN1
|
|
is_part_of
|
NMDA receptor complex (GRIN1, GRIN2B)
|
|
|
|
Neurological
|
16,164
|
156334 |
CNR2
|
|
interacts (colocalizes) with
|
GRIN1
|
|
156335 |
GRIN1
|
|
is_part_of
|
NMDA receptor complex
|
|
156366 |
GRIN1
|
|
is_part_of
|
NMDA receptor complex (GRIN1A, GRIN2B), tetrameric
|
|
|
|
Neurological
Alzheimer disease
|
16,174
|
156369 |
GRIN1
|
|
is_part_of
|
NMDA receptor complex (GRIN1, GRIN2C), tetrameric
|
|
156375 |
GRIN1
|
|
is_part_of
|
NMDA receptor complex (GRIN1, GRIN2A, GRIN2C), tetrameric
|
|
156380 |
GRIN1
|
|
is_part_of
|
NMDA receptor complex (GRIN1, GRIN2D), tetrameric
|
|
|
|
Neurological
|
16,178
|
156386 |
GRIN1
|
|
affects_activity of
|
NMDA receptor complex
|
|
|
|
Neurological
Metabolic
|
16,185
|
156551 |
SPTA1
|
|
interacts (colocalizes) with
|
GRIN1
|
in rat; concerning NR1A
|
156556 |
GRIN1-phos
|
|
affects_activity of
|
GRIN1
|
in rat; concerning NR1A
|
|
|
Neurological
|
16,187
|
156566 |
ACTN2
|
|
interacts (colocalizes) with
|
GRIN1
|
via binding by its central rod domain to the cytoplasmic tail of NR1
|
156571 |
GRIN1
|
|
is_part_of
|
ACTN2-GRIN1 complex
|
|
156575 |
DLG4
|
NOT |
interacts (colocalizes) with
|
GRIN1
|
|
|
|
Neurological
|
16,188
|
156582 |
GRIN3A
|
|
interacts (colocalizes) with
|
GRIN1
|
in cerebrocortical mouse extracts
|
156585 |
GRIN1
|
|
is_part_of
|
NMDA receptor complex (GRIN1, GRIN3A)
|
in cerebrocortical mouse extracts
|
|
|
Neurological
|