|
1,394
|
| 9939 |
Schizophrenia
|
|
decreases_expression of
|
GLP1R
|
|
|
16223876
|
Schizophrenia
|
|
2,046
|
| 16340 |
Exenatide
|
|
increases_activity of
|
GLP1R
|
|
|
18787107
|
Diabetes mellitus, type II
Insulin resistance
|
|
2,451
|
| 22686 |
Diabetes mellitus, type II
|
|
decreases_expression of
|
GLP1R
|
in pancreas, in pancreatic islets
|
| 22688 |
TCF7L2
|
|
affects_expression of
|
GLP1R
|
in pancreas, in pancreatic islets
|
|
19386626
|
Diabetes mellitus, type II
Insulin resistance
|
|
2,784
|
| 25734 |
Metformin
|
|
increases_expression of
|
GLP1R
|
in pancreas, in pancreatic islets
|
|
20972533
|
Diabetes mellitus, type II
Insulin resistance
|
|
2,786
|
| 25759 |
Glucagon-like peptide 1
|
|
increases_activity of
|
GLP1R
|
|
| 62835 |
GLP1R
|
|
affects_activity of
|
glucose homeostasis
|
|
| 62836 |
GLP1R
|
|
affects_activity of
|
abnormal circulating insulin level
|
|
|
21673955
|
Diabetes mellitus, type II
Insulin resistance
|
|
4,869
|
| 47997 |
Abeta42-Al complex
|
|
increases_expression of
|
GLP1R
|
|
|
21298039
|
Alzheimer disease
|
|
5,736
|
| 54317 |
SOX17
|
|
decreases_expression of
|
GLP1R
|
in pancreas, in pancreatic beta cells
|
|
25144761
|
Diabetes mellitus, type II
Insulin resistance
|
|
5,783
|
| 54562 |
Glucagon-like peptide 1
|
|
increases_activity of
|
GLP1R
|
in pancreas, in pancreatic beta cells
|
| 54563 |
GLP1R
|
|
increases_quantity of
|
cAMP
|
in pancreas, in pancreatic beta cells
|
|
25697093
|
Diabetes mellitus, type II
Insulin resistance
|
|
6,130
|
| 57432 |
response to hypoxia
|
|
decreases_expression of
|
GLP1R
|
|
|
25503986
|
Diabetes mellitus, type II
Insulin resistance
|
|
6,456
|
| 61144 |
Metformin
|
|
increases_expression of
|
GLP1R
|
in pancreatic islet
|
| 61939 |
GLP1R
|
|
increases_activity of
|
incretin hormone signaling
|
|
|
22117616
|
Diabetes mellitus, type II
Cancer
Insulin resistance
|
|
7,357
|
| 72264 |
GLP1R
|
|
increases_activity of
|
insulin secretion
|
|
|
26395740
|
Cardiovascular
|
|
7,531
|
| 75134 |
Glucagon-like peptide 1
|
|
increases_activity of
|
GLP1R
|
|
| 75136 |
GLP1R
|
|
increases_activity of
|
Adenylate cyclase
|
|
|
28275047
|
Diabetes mellitus, type II
Insulin resistance
|
|
8,021
|
| 79799 |
GLP1R
|
|
is_expressed_in
|
pancreas
|
|
| 79800 |
GLP1R
|
|
is_expressed_in
|
lung
|
|
| 79801 |
GLP1R
|
|
is_expressed_in
|
adipose tissue
|
|
| 79802 |
GLP1R
|
|
is_expressed_in
|
kidney
|
|
| 79803 |
GLP1R
|
|
is_expressed_in
|
heart
|
|
| 79804 |
GLP1R
|
|
is_expressed_in
|
vascular smooth muscle
|
|
| 79805 |
GLP1R
|
|
is_expressed_in
|
central nervous system
|
|
| 79806 |
GLP1R
|
|
increases_quantity of
|
cAMP
|
|
| 79808 |
GLP1R
|
|
increases_activity of
|
Protein kinase A
|
|
| 79809 |
GLP1R
|
|
increases_activity of
|
RAPGEF4
|
|
| 79810 |
GLP1R
|
|
affects_expression of
|
INS
|
|
| 79812 |
GLP1R
|
|
affects_expression of
|
SLC2A2
|
|
| 79814 |
GLP1R
|
|
affects_activity of
|
ATP-sensitive potassium channel complex
|
|
| 79816 |
GLP1R
|
|
affects_expression of
|
NAPA
|
|
| 79817 |
GLP1R
|
|
increases_activity of
|
ERK1 and ERK2 cascade
|
|
| 79818 |
GLP1R
|
|
increases_activity of
|
phosphatidylinositol 3-kinase signaling
|
|
|
25834231
|
Diabetes mellitus, type II
Insulin resistance
|
|
12,207
|
| 119895 |
Liraglutide
|
|
increases_activity of
|
GLP1R
|
|
|
32294179
|
Diabetes mellitus, type II
Insulin resistance
COVID-19
|
|
15,707
|
| 148822 |
GLP1R agonist
|
|
increases_activity of
|
GLP1R
|
|
|
|
Alzheimer disease
|
|
16,124
|
| 155898 |
GLP1R
|
|
is_expressed_in
|
kidney
|
|
| 155908 |
GLP1R
|
|
affects_activity of
|
Nephropathy, diabetic
|
|
| 155909 |
GLP1R
|
|
decreases_activity of
|
inflammatory response
|
|
| 155910 |
GLP1R
|
|
decreases_activity of
|
renal fibrosis
|
|
| 155911 |
Diabetes mellitus, type II
|
|
decreases_expression of
|
GLP1R
|
in renal glomeruli
|
| 155912 |
Exenatide
|
|
affects_activity of
|
GLP1R
|
in renal glomeruli
|
|
|
Diabetes mellitus, type II
Insulin resistance
|
|
16,127
|
| 155999 |
VIP (1-27)
|
NOT |
increases_activity of
|
GLP1R
|
|
|
|
Diabetes mellitus, type II
Insulin resistance
|
|
16,131
|
| 156035 |
GLP1R
|
|
is_expressed_in
|
brain
|
|
| 156036 |
GLP1R
|
|
increases_activity of
|
regulation of appetite
|
|
| 156037 |
GLP1R
|
|
increases_activity of
|
regulation of gastric motility
|
|
| 156038 |
GLP1R
|
|
affects_activity of
|
heart
|
|
|
|
Diabetes mellitus, type II
Insulin resistance
Metabolic syndrome
|
|
16,175
|
| 156390 |
GLP1R
|
|
is_part_of
|
GLP1R homodimer
|
|
| 156391 |
GLP1R
|
|
is_part_of
|
GLP1R-SCTR complex
|
|
|
|
Diabetes mellitus, type II
Insulin resistance
|
|
16,176
|
| 156426 |
hyperglycemia
|
|
decreases_activity of
|
GLP1R
|
|
| 156432 |
GLP1R agonist
|
|
increases_activity of
|
GLP1R
|
|
| 156435 |
GLP1R
|
|
is_expressed_in
|
pancreatic beta cell
|
|
| 156437 |
GLP1R
|
|
increases_activity of
|
insulin secretion involved in cellular response to glucose stimulus
|
in pancreatic beta cells
|
| 156439 |
GLP1R
|
|
decreases_activity of
|
type B pancreatic cell apoptotic process
|
|
| 156443 |
GLP1R
|
|
increases_activity of
|
Adenylate cyclase
|
|
| 156451 |
GLP1R
|
|
increases_activity of
|
EGFR
|
|
| 156454 |
Exenatide
|
|
increases_activity of
|
GLP1R
|
|
| 156455 |
Liraglutide
|
|
increases_activity of
|
GLP1R
|
|
|
|
Diabetes mellitus, type II
Insulin resistance
|
|
16,177
|
| 156378 |
GLP1R
|
|
is localized in
|
membrane
|
|
| 156467 |
Glucagon-like peptide 1
|
|
increases_activity of
|
GLP1R
|
|
| 156468 |
GLP1R
|
|
affects_activity of
|
Diabetes mellitus, type II
|
|
| 156469 |
GLP1R
|
|
affects_activity of
|
Obesity
|
|
| 156472 |
GLP1R
|
|
increases_activity of
|
insulin secretion involved in cellular response to glucose stimulus
|
|
| 156473 |
GLP1R
|
|
increases_activity of
|
insulin processing
|
|
| 156474 |
GLP1R
|
|
decreases_activity of
|
glucagon secretion
|
|
| 156475 |
GLP1R
|
|
decreases_activity of
|
intestinal motility
|
|
| 156476 |
GLP1R
|
|
decreases_activity of
|
gastric motility
|
|
| 156477 |
GLP1R
|
|
increases_activity of
|
regulation of appetite
|
|
| 156478 |
GLP1R
|
|
affects_activity of
|
kidney
|
|
| 156479 |
GLP1R
|
|
affects_quantity of
|
Lipid
|
in blood
|
| 156480 |
GLP1R
|
|
decreases_quantity of
|
TNF
|
in blood
|
| 156482 |
GLP1R agonist
|
|
increases_activity of
|
GLP1R
|
|
| 156483 |
GLP1R
|
|
increases_quantity of
|
cAMP
|
|
| 156484 |
GLP1R
|
|
increases_activity of
|
Protein kinase A
|
via cAMP
|
| 156485 |
GLP1R
|
|
increases_activity of
|
RAPGEF4
|
via cAMP
|
| 156486 |
GLP1R
|
|
increases_activity of
|
ERK1 and ERK2 cascade
|
|
| 156487 |
GLP1R
|
|
increases_activity of
|
protein kinase B signaling
|
|
| 156488 |
GLP1R
|
|
interacts (colocalizes) with
|
ARRB1
|
|
| 156489 |
GLP1R
|
|
interacts (colocalizes) with
|
ARRB2
|
|
| 156494 |
GLP1R
|
|
interacts (colocalizes) with
|
GNAS
|
|
| 156495 |
GLP1R
|
|
interacts (colocalizes) with
|
GNAQ
|
|
| 156496 |
GLP1R
|
|
interacts (colocalizes) with
|
GNAQ
|
|
| 156497 |
GLP1R
|
|
interacts (colocalizes) with
|
GNAI1
|
|
| 156498 |
GLP1R
|
|
interacts (colocalizes) with
|
GNAO1
|
|
| 156499 |
receptor internalization
|
|
affects_activity of
|
GLP1R
|
|
| 156505 |
GLP1R
|
|
interacts (colocalizes) with
|
CAV1
|
|
| 156521 |
GLP1R
|
|
affects_activity of
|
insulin granule exocytosis
|
in pancreatic beta cells
|
| 156523 |
GLP1R
|
|
interacts (colocalizes) with
|
Adenylate cyclase
|
|
| 156524 |
Tirzepatide
|
|
increases_activity of
|
GLP1R
|
|
|
|
Diabetes mellitus, type II
Insulin resistance
|
|
16,183
|
| 156538 |
GLP1R
|
|
is_part_of
|
CAV1-GLP1R complex
|
in HEK293 cells
|
| 156541 |
GLP1R
|
|
is localized in
|
plasma membrane
|
in HEK293 cells; in resting cells
|
| 156542 |
GLP1R
|
|
is localized in
|
cytoplasm
|
in HEK293 cells; in resting cells
|
| 156545 |
ARRB2
|
NOT |
affects_activity of
|
GLP1R
|
in HEK293 cells; via receptor internalization
|
|
|
Diabetes mellitus, type II
Insulin resistance
|
|
16,186
|
| 156558 |
GIPR
|
|
affects_activity of
|
GLP1R
|
in HEK-293T cells
|
| 156559 |
GLP2R
|
NOT |
affects_activity of
|
GLP1R
|
in HEK-293T cells
|
| 156560 |
GCGR
|
NOT |
affects_activity of
|
GLP1R
|
in HEK-293T cells
|
| 156561 |
PTH1R
|
NOT |
affects_activity of
|
GLP1R
|
in HEK-293T cells
|
| 156562 |
GIPR
|
|
decreases_quantity of
|
GLP1R
|
in membrane
|
|
|
Diabetes mellitus, type II
Insulin resistance
|
CIDeRplus