|
1,989
|
| 15662 |
ACE inhibitor
|
|
affects_activity of
|
Bradykinin
|
|
| 15665 |
Bradykinin
|
|
increases_activity of
|
increased insulin sensitivity
|
in skeletal muscle
|
| 15666 |
Bradykinin
|
|
increases_activity of
|
glucose import
|
in skeletal muscle, in cardiac muscle
|
| 15667 |
Bradykinin
|
|
increases_activity of
|
BDKRB2
|
in skeletal muscle
|
| 15674 |
ACE
|
|
decreases_quantity of
|
Bradykinin
|
|
| 15678 |
ACE inhibitor
|
|
increases_quantity of
|
Bradykinin
|
|
|
20809236
|
Diabetes mellitus, type II
Stroke, ischemic
Myocardial infarction
Insulin resistance
Cardiovascular disease
Nephropathy, diabetic
Retinopathy, diabetic
Neuropathy, diabetic
|
|
1,990
|
| 15699 |
Bradykinin
|
|
increases_activity of
|
glucose import
|
in skeletal muscle; if insulin-stimulated
|
| 15700 |
Bradykinin
|
|
increases_transport of
|
SLC2A4
|
in skeletal muscle; to the plasma membrane; if induced by insulin
|
| 15701 |
Bradykinin
|
|
decreases_phosphorylation of
|
Insulin receptor beta subunit
|
in skeletal muscle; if induced by insulin
|
| 15702 |
Bradykinin
|
|
decreases_phosphorylation of
|
IRS1
|
in skeletal muscle; if induced by insulin
|
|
9539311
|
Diabetes mellitus, type II
Insulin resistance
|
|
1,991
|
| 15703 |
Bradykinin
|
|
increases_transport of
|
SLC2A4
|
to the plasma membrane
|
| 15704 |
Bradykinin
|
|
increases_transport of
|
SLC2A1
|
to the plasma membrane
|
|
852980
|
Diabetes mellitus, type II
Insulin resistance
|
|
2,056
|
| 16595 |
ACE
|
|
decreases_quantity of
|
Bradykinin
|
|
|
2440624
|
Diabetes mellitus, type II
Insulin resistance
|
|
2,525
|
| 23525 |
Bradykinin
|
|
decreases_expression of
|
NOS2
|
if Abeta-induced expression
|
| 23526 |
Bradykinin
|
|
decreases_expression of
|
PTGS2
|
if Abeta-induced expression
|
| 23550 |
Bradykinin
|
|
affects_activity of
|
inflammatory response
|
|
|
20937084
|
Alzheimer disease
|
|
3,828
|
| 38302 |
Enalaprilat
|
|
affects_quantity of
|
Bradykinin
|
in blood serum
|
|
11406494
|
Diabetes mellitus, type II
Insulin resistance
|
|
4,704
|
| 46660 |
Bradykinin
|
|
increases_quantity of
|
NO
|
|
|
3131684
|
Metabolic
Cardiovascular disease
|
|
5,031
|
| 49607 |
ACE inhibitor
|
|
increases_activity of
|
Bradykinin
|
in arteries
|
|
12208785
|
Diabetes mellitus, type II
Insulin resistance
|
|
6,523
|
| 62378 |
Bradykinin
|
|
increases_activity of
|
abnormal vascular endothelial cell physiology
|
|
|
18177481
|
Diabetes mellitus, type II
Insulin resistance
Cardiomyopathy, diabetic
|
|
7,884
|
| 78423 |
Bradykinin
|
|
decreases_activity of
|
cellular senescence
|
in endothelial cells
|
|
19075096
|
Atherosclerosis
|
|
7,885
|
| 78425 |
MASP1
|
|
increases_quantity of
|
Bradykinin
|
|
|
21625439
|
Cardiovascular disease
|
|
7,887
|
| 78599 |
Bradykinin
|
|
increases_activity of
|
inflammatory response
|
|
| 78600 |
Bradykinin
|
|
increases_activity of
|
vasodilation
|
|
| 78622 |
Plasma kallikrein
|
|
increases_quantity of
|
Bradykinin
|
|
| 78623 |
Kininogen, high-molecular-weight
|
|
affects_quantity of
|
Bradykinin
|
via cleavage by plasma kallikrein
|
| 78624 |
plasma kallikrein-kinin cascade
|
|
increases_activity of
|
Bradykinin
|
|
| 78625 |
Bradykinin
|
|
increases_quantity of
|
NO
|
|
| 78626 |
Bradykinin
|
|
increases_activity of
|
positive regulation of urine volume
|
|
| 78627 |
Bradykinin
|
|
increases_activity of
|
pressure natriuresis
|
|
|
19689262
|
Cardiovascular disease
|
|
9,551
|
| 101278 |
VAV2
|
|
affects_quantity of
|
Bradykinin
|
|
|
17202406
|
Cardiovascular disease
|
|
11,709
|
| 116216 |
ACE inhibitor
|
|
increases_quantity of
|
Bradykinin
|
in blood
|
| 116218 |
Bradykinin
|
|
increases_activity of
|
cough
|
|
| 116219 |
Bradykinin
|
|
increases_activity of
|
angioedema
|
|
| 116220 |
Bradykinin
|
|
increases_activity of
|
vasodilation
|
|
| 116222 |
Bradykinin
|
|
increases_quantity of
|
NO
|
|
| 116223 |
Bradykinin
|
|
increases_activity of
|
prostaglandin biosynthetic process
|
|
|
29598869
|
Cardiovascular disease
|
|
12,020
|
| 117801 |
ACE
|
|
decreases_quantity of
|
Bradykinin
|
|
| 117805 |
Bradykinin
|
|
increases_activity of
|
vasodilation
|
|
|
30934934
|
Diabetes mellitus, type II
Insulin resistance
Cardiovascular disease
|
|
12,030
|
| 117990 |
CMA1
|
NOT |
decreases_quantity of
|
Bradykinin
|
in heart left ventricle
|
|
2266130
|
Cardiovascular disease
|
|
12,056
|
| 118259 |
ACE
|
|
decreases_activity of
|
Bradykinin
|
in blood
|
| 118288 |
Bradykinin
|
|
increases_phosphorylation of
|
ACE
|
at Ser1270 of ACE
|
| 118290 |
Bradykinin
|
|
increases_expression of
|
ACE
|
via phosphorylation of ACE at Ser1270
|
| 118292 |
Bradykinin
|
|
increases_expression of
|
PTGS2
|
via phosphorylation of ACE at Ser1270
|
| 118294 |
ACE2
|
NOT |
decreases_quantity of
|
Bradykinin
|
|
| 118351 |
Angiotensin (1-9)
|
|
increases_activity of
|
Bradykinin
|
|
|
19065996
|
Diabetes mellitus, type II
Insulin resistance
|
|
12,064
|
| 118384 |
Bradykinin
|
|
decreases_activity of
|
vasoconstriction
|
|
| 118387 |
Angiotensin (1-7)
|
|
increases_activity of
|
Bradykinin
|
|
| 118397 |
ACE inhibitor
|
|
increases_quantity of
|
Bradykinin
|
|
| 118457 |
ACE inhibitor
|
|
increases_quantity of
|
Bradykinin
|
|
|
19065996
|
Diabetes mellitus, type II
Insulin resistance
|
|
12,082
|
| 118693 |
ACE
|
|
decreases_quantity of
|
Bradykinin
|
|
| 118694 |
Bradykinin
|
|
increases_activity of
|
vasodilation
|
|
| 118695 |
Bradykinin
|
|
increases_activity of
|
PLAT
|
|
| 118704 |
ACE inhibitor
|
|
increases_quantity of
|
Bradykinin
|
|
|
32348783
|
Cardiovascular disease
COVID-19
|
|
12,178
|
| 119342 |
Bradykinin
|
|
increases_activity of
|
kallikrein-kinin system
|
|
| 119347 |
Bradykinin
|
|
interacts (colocalizes) with
|
BDKRB2
|
|
|
32544563
|
COVID-19
|
|
12,182
|
| 119460 |
KLK1
|
|
increases_quantity of
|
Bradykinin
|
in plasma
|
|
31133046
|
Inflammation
|
|
13,042
|
| 124248 |
MME
|
|
affects_quantity of
|
Bradykinin
|
|
|
31089754
|
Diabetes mellitus, type II
Insulin resistance
Cardiomyopathy, diabetic
|
|
13,947
|
| 131843 |
ACE
|
|
decreases_quantity of
|
Bradykinin
|
|
| 131845 |
Bradykinin
|
|
increases_activity of
|
vasodilation
|
|
| 131848 |
Bradykinin
|
|
increases_activity of
|
prostaglandin biosynthetic process
|
|
| 131849 |
Bradykinin
|
|
increases_activity of
|
nitric oxide biosynthetic process
|
|
| 131850 |
Bradykinin
|
|
decreases_activity of
|
vascular smooth muscle cell proliferation
|
|
|
33486116
|
COVID-19
|
|
14,067
|
| 132947 |
ACE
|
|
decreases_quantity of
|
Bradykinin
|
|
| 132948 |
ACE inhibitor
|
|
increases_quantity of
|
Bradykinin
|
|
| 132949 |
Bradykinin
|
|
increases_activity of
|
chymase pathway
|
in heart, in lung
|
|
33169633
|
COVID-19
|
|
14,078
|
| 133028 |
ACE2
|
NOT |
decreases_quantity of
|
Bradykinin
|
|
|
32264791
|
COVID-19
|
|
14,159
|
| 133879 |
ACE
|
|
decreases_quantity of
|
Bradykinin
|
|
| 133880 |
Bradykinin
|
|
affects_activity of
|
inflammatory response
|
|
|
23213621
|
Parkinson disease
|
|
14,189
|
| 133993 |
AGTR2
|
|
affects_quantity of
|
Bradykinin
|
|
|
15534073
|
Renal
|
|
14,205
|
| 134092 |
ANPEP
|
NOT |
decreases_quantity of
|
Bradykinin
|
|
|
1978675
|
Cardiovascular disease
|
|
14,302
|
| 134984 |
Angiotensin (1-7)
|
|
increases_activity of
|
Bradykinin
|
via ACE inhibition
|
| 134985 |
ACE
|
|
decreases_activity of
|
Bradykinin
|
|
| 135016 |
ACE inhibitor
|
|
increases_activity of
|
Bradykinin
|
|
| 135017 |
Bradykinin
|
|
increases_activity of
|
vasodilation
|
|
|
32305401
|
Cardiovascular disease
COVID-19
|
CIDeRplus