|
11,748
|
| 116368 |
Angiotensin II
|
|
increases_quantity of
|
Angiotensin IV
|
via cleavage by aminopeptidases
|
| 116372 |
Angiotensin IV
|
|
increases_activity of
|
AGTR1
|
|
|
32333398
|
COVID-19
|
|
11,921
|
| 117264 |
ANPEP
|
|
increases_quantity of
|
Angiotensin IV
|
in hypothalamus
|
| 119257 |
Angiotensin III
|
|
increases_quantity of
|
Angiotensin IV
|
in hypothalamus
|
|
8876246
|
Cardiovascular disease
|
|
11,933
|
| 117314 |
Angiotensin IV
|
|
interacts (colocalizes) with
|
AGTR2
|
in HEK293 cells
|
|
21542804
|
Cardiovascular disease
|
|
12,029
|
| 118027 |
Angiotensin IV
|
|
increases_activity of
|
MAS1
|
|
|
30934934
|
Diabetes mellitus, type II
Insulin resistance
Cardiovascular disease
|
|
12,035
|
| 118091 |
ANPEP
|
|
increases_quantity of
|
Angiotensin IV
|
|
| 118092 |
Angiotensin IV
|
|
increases_activity of
|
LNPEP
|
|
| 118105 |
Angiotensin IV
|
|
increases_activity of
|
AGTR1
|
|
| 118133 |
Angiotensin IV
|
|
increases_quantity of
|
Angiotensin (3-7)
|
|
|
30934934
|
Diabetes mellitus, type II
Insulin resistance
Cardiovascular disease
|
|
12,039
|
| 118109 |
Angiotensin IV
|
|
interacts (colocalizes) with
|
LNPEP
|
|
|
11707427
|
Cardiovascular disease
|
|
12,056
|
| 118330 |
ANPEP
|
|
increases_quantity of
|
Angiotensin IV
|
|
| 118331 |
Angiotensin IV
|
|
increases_activity of
|
learning or memory
|
|
| 118332 |
Angiotensin IV
|
|
decreases_activity of
|
abnormal temporal memory
|
|
| 118333 |
Angiotensin IV
|
|
decreases_activity of
|
sodium ion transport
|
in kidney, in renal proximal tubules
|
| 118334 |
Angiotensin IV
|
|
affects_activity of
|
regulation of blood pressure
|
|
| 118335 |
Angiotensin IV
|
|
increases_activity of
|
LNPEP
|
|
| 118336 |
Angiotensin IV
|
|
increases_activity of
|
AGTR1
|
|
| 118341 |
Angiotensin IV
|
|
increases_quantity of
|
Angiotensin (3-7)
|
|
|
19065996
|
Diabetes mellitus, type II
Insulin resistance
|
|
12,057
|
| 118226 |
Angiotensin IV
|
|
decreases_activity of
|
Myocardial infarction
|
|
| 118227 |
Angiotensin IV
|
|
increases_activity of
|
LNPEP
|
|
| 118232 |
Angiotensin IV
|
|
decreases_quantity of
|
BAX
|
|
| 118233 |
Angiotensin IV
|
|
decreases_quantity of
|
CASP3
|
|
| 118234 |
Angiotensin IV
|
|
decreases_quantity of
|
CASP9
|
|
| 118235 |
Angiotensin IV
|
|
increases_quantity of
|
BCL2
|
|
| 118239 |
Angiotensin IV
|
|
decreases_quantity of
|
TNF
|
|
| 118240 |
Angiotensin IV
|
|
decreases_quantity of
|
MMP9
|
|
| 118241 |
Angiotensin IV
|
|
decreases_quantity of
|
VCAM1
|
|
| 118242 |
Angiotensin IV
|
|
increases_phosphorylation of
|
AKT1
|
|
| 118243 |
Angiotensin IV
|
|
increases_phosphorylation of
|
MTOR
|
|
| 118244 |
Angiotensin IV
|
|
decreases_activity of
|
apoptotic process
|
via LNPEP
|
| 118245 |
Angiotensin IV
|
|
affects_activity of
|
phosphatidylinositol 3-kinase signaling
|
via LNPEP
|
| 118246 |
Angiotensin IV
|
|
affects_activity of
|
TOR signaling
|
via LNPEP
|
| 118250 |
Angiotensin IV
|
|
decreases_activity of
|
inflammatory response
|
via LNPEP
|
|
27038740
|
Cardiovascular disease
|
|
12,058
|
| 118253 |
Angiotensin IV
|
|
increases_activity of
|
vasodilation
|
via LNPEP
|
|
9493859
|
Cardiovascular disease
|
|
12,087
|
| 118745 |
Angiotensin IV
|
|
increases_expression of
|
SERPINE1
|
in proximal tubular epithelial cells
|
|
10432384
|
Cardiovascular disease
|
|
12,088
|
| 118750 |
Angiotensin IV
|
NOT |
increases_expression of
|
SERPINE1
|
in renal tubular epithelial cell
|
|
17444273
|
Cardiovascular disease
|
|
12,089
|
| 118751 |
Angiotensin IV
|
|
increases_expression of
|
SERPINE1
|
in aortic endothelial cells
|
|
7593643
|
Cardiovascular disease
|
|
12,194
|
| 119794 |
Angiotensin III
|
|
increases_quantity of
|
Angiotensin IV
|
via aminopeptidase
|
| 119795 |
Angiotensin II
|
|
increases_quantity of
|
Angiotensin IV
|
via dipeptidyl aminopeptidase
|
| 119796 |
Angiotensin IV
|
|
increases_activity of
|
LNPEP
|
|
|
32127770
|
Neurodegenerative disorder
|
|
14,067
|
| 132932 |
Angiotensin IV
|
|
increases_activity of
|
COVID-19, severe
|
|
| 132952 |
chymase pathway
|
|
increases_quantity of
|
Angiotensin IV
|
|
| 132959 |
ANPEP
|
|
increases_quantity of
|
Angiotensin IV
|
|
| 132965 |
Angiotensin IV
|
|
increases_activity of
|
LNPEP
|
|
| 132966 |
Angiotensin IV
|
|
increases_activity of
|
vasodilation
|
via LNPEP
|
| 132967 |
Angiotensin IV
|
|
increases_activity of
|
renal sodium excretion
|
via LNPEP
|
| 132968 |
Angiotensin IV
|
|
increases_activity of
|
nitric oxide biosynthetic process
|
via LNPEP
|
| 132969 |
Angiotensin IV
|
|
increases_activity of
|
vasoconstriction
|
via AGTR1
|
| 132970 |
Angiotensin IV
|
|
increases_activity of
|
AGTR1
|
|
| 132971 |
Angiotensin IV
|
|
increases_activity of
|
thrombosis
|
via SERPINE1
|
| 132972 |
Angiotensin IV
|
|
increases_activity of
|
SERPINE1
|
|
| 132973 |
Angiotensin IV
|
|
increases_activity of
|
LNPEP
|
|
|
33169633
|
COVID-19
|
|
14,152
|
| 133716 |
Angiotensin IV
|
|
increases_activity of
|
increased cerebral blood flow rate
|
via increased NO release
|
| 133780 |
Angiotensin IV
|
|
increases_activity of
|
nitric oxide biosynthetic process
|
in brain
|
| 133781 |
Angiotensin IV
|
|
increases_quantity of
|
NO
|
in brain
|
|
9712180
|
Neurodegenerative disorder
|
|
14,159
|
| 133794 |
Angiotensin IV
|
|
increases_activity of
|
increased cerebral blood flow rate
|
in brain microvessels
|
| 133795 |
Angiotensin II
|
|
increases_quantity of
|
Angiotensin IV
|
in neurons
|
| 133827 |
Angiotensin IV
|
|
increases_activity of
|
dopamine secretion
|
in striatum
|
| 133857 |
Angiotensin IV
|
|
increases_activity of
|
acetylcholine secretion
|
in hippocampus
|
|
23213621
|
Parkinson disease
|
|
14,168
|
| 133894 |
Angiotensin IV
|
|
decreases_activity of
|
SNCA
|
|
|
17900533
|
Neurodegenerative disorder
|
|
14,183
|
| 133973 |
Angiotensin IV
|
|
increases_activity of
|
synaptic transmission, cholinergic
|
in hippocampus
|
|
11249971
|
Neurodegenerative disorder
|
|
14,197
|
| 134045 |
Angiotensin IV
|
|
increases_activity of
|
dopamine secretion
|
|
| 134046 |
Angiotensin IV
|
|
increases_activity of
|
serotonin secretion
|
|
| 134047 |
Angiotensin IV
|
|
decreases_activity of
|
seizures
|
in the acute pilocarpine rat seizure model
|
|
16771832
|
Epilepsy
|
|
14,199
|
| 134065 |
Angiotensin IV
|
|
increases_activity of
|
NF-kappaB complex
|
in vascular smooth muscle cells
|
|
15831814
|
Cardiovascular disease
|
|
14,200
|
| 134066 |
Angiotensin IV
|
|
increases_activity of
|
NF-kappaB complex
|
in vascular smooth muscle cells; via LNPEP (AT4)
|
| 134068 |
Angiotensin IV
|
|
increases_expression of
|
CCL2
|
in vascular smooth muscle cells; via LNPEP (AT4)
|
| 134069 |
Angiotensin IV
|
|
increases_expression of
|
IL6
|
in vascular smooth muscle cells; via LNPEP (AT4)
|
| 134070 |
Angiotensin IV
|
|
increases_expression of
|
TNF
|
in vascular smooth muscle cells; via LNPEP (AT4)
|
| 134071 |
Angiotensin IV
|
|
increases_expression of
|
ICAM1
|
in vascular smooth muscle cells; via LNPEP (AT4)
|
| 134072 |
Angiotensin IV
|
|
increases_expression of
|
ICAM1
|
in vascular smooth muscle cells; via LNPEP (AT4)
|
| 134073 |
Angiotensin IV
|
|
increases_activity of
|
inflammatory response
|
in vascular smooth muscle cells; via LNPEP (AT4)
|
|
15831814
|
Cardiovascular disease
|
|
14,203
|
| 134082 |
LNPEP
|
NOT |
decreases_quantity of
|
Angiotensin IV
|
|
|
17684103
|
Cardiovascular disease
|
|
14,206
|
| 134093 |
Angiotensin IV
|
|
increases_activity of
|
Phosphatidylinositol 3-kinase
|
in pulmonary artery endothelial cells
|
| 134112 |
Angiotensin IV
|
|
increases_activity of
|
PDK1
|
in pulmonary artery endothelial cells
|
| 134113 |
Angiotensin IV
|
|
increases_activity of
|
AKT1
|
in pulmonary artery endothelial cells
|
| 134114 |
Angiotensin IV
|
|
increases_activity of
|
RPS6KB1
|
in pulmonary artery endothelial cells
|
| 134115 |
Angiotensin IV
|
|
increases_activity of
|
ERK1 and ERK2 cascade
|
in pulmonary artery endothelial cells; via phosphorylation of ERK1/ERK2
|
| 134116 |
Angiotensin IV
|
|
increases_activity of
|
DNA biosynthetic process
|
in pulmonary artery endothelial cells
|
| 134117 |
Angiotensin IV
|
|
increases_activity of
|
vascular endothelial cell proliferation
|
in pulmonary artery endothelial cells
|
|
12225947
|
Cardiovascular disease
|
|
14,207
|
| 134123 |
Angiotensin III
|
|
increases_quantity of
|
Angiotensin IV
|
in brain; via ANPEP (APN)
|
|
11295571
|
Cardiovascular disease
|
|
14,210
|
| 134100 |
Angiotensin IV
|
|
increases_activity of
|
memory
|
|
| 134144 |
Angiotensin IV
|
|
increases_activity of
|
angiotensin-mediated drinking behavior
|
|
|
22590974
|
Cardiovascular disease
|
|
14,212
|
| 134118 |
Angiotensin IV
|
|
increases_quantity of
|
cGMP
|
|
| 134119 |
Angiotensin IV
|
|
increases_activity of
|
vasodilation
|
in pulmonary artery cells; via AngIV receptor
|
| 134120 |
Angiotensin IV
|
|
affects_activity of
|
calcium-mediated signaling using intracellular calcium source
|
in pulmonary artery cells
|
|
11053019
|
Cardiovascular disease
|
|
14,227
|
| 134265 |
Angiotensin IV
|
|
increases_activity of
|
melatonin biosynthetic process
|
in pinealocytes
|
|
30222958
|
Diabetes mellitus, type II
Insulin resistance
|
|
14,231
|
| 134369 |
ANPEP
|
|
increases_quantity of
|
Angiotensin IV
|
|
| 134372 |
Angiotensin IV
|
|
increases_activity of
|
LNPEP
|
|
| 134374 |
Angiotensin IV
|
|
increases_quantity of
|
Angiotensin (3-4)
|
in blood plasma
|
|
30978131
|
Cardiovascular disease
|
|
14,423
|
| 136138 |
Angiotensin IV
|
|
increases_activity of
|
LNPEP
|
in LLC-PK1 kidney cell line
|
|
17634404
|
Renal
|
CIDeRplus