Search Results for "ACE" - 279 interactions found in 95 entries.

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Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
1,970
15436 macrophage differentiation increases_expression of ACE
15437 adipocyte-conditioned medium increases_expression of ACE in macrophages
15447 ACE decreases_activity of positive regulation of cytokine production involved in inflammatory response in macrophages
15448 M1 macrophage decreases_expression of ACE
15449 M2 macrophage increases_expression of ACE
15451 AMPK increases_expression of ACE
45706 IL4 increases_expression of ACE via increased M2 macrophage activity
45707 IL13 increases_expression of ACE via increased M2 macrophage activity
45708 Lipopolysaccharide decreases_expression of ACE via increased M1 macrophage activity
45709 IFNG decreases_expression of ACE via increased M1 macrophage activity
21116821 Diabetes mellitus, type II
Insulin resistance
1,985
15581 Enalaprilat decreases_activity of ACE
9498644 Diabetes mellitus, type II
Insulin resistance
1,987
15594 fat cell differentiation increases_expression of ACE in adipose tissue
12031955 Diabetes mellitus, type II
Insulin resistance
1,988
15612 Glucose increases_expression of ACE in pancreas, in pancreatic islets
15614 Zofenopril decreases_activity of ACE
15615 Enalaprilat decreases_activity of ACE
15617 Zofenopril NOT increases_expression of ACE in pancreas, in pancreatic islets; after glucose stimulation
15620 Enalaprilat NOT increases_expression of ACE in pancreas, in pancreatic islets; after glucose stimulation
16452552 Diabetes mellitus, type II
Insulin resistance
1,989
15673 ACE increases_quantity of Angiotensin II
15674 ACE decreases_quantity of Bradykinin
15675 ACE decreases_quantity of NO
15676 ACE inhibitor decreases_activity of ACE
20809236 Diabetes mellitus, type II
Stroke, ischemic
Myocardial infarction
Insulin resistance
Cardiovascular disease
Nephropathy, diabetic
Retinopathy, diabetic
Neuropathy, diabetic
2,020
16003 hypertension increases_expression of ACE in adipose tissue; in obese probands
16008 Cortisol NOT affects_expression of ACE in adipose tissue
16012 Insulin NOT affects_expression of ACE in adipose tissue
16017 Estradiol NOT affects_expression of ACE in adipose tissue
16022 Triiodothyronine NOT affects_expression of ACE in adipose tissue
16027 Angiotensin II NOT affects_expression of ACE in adipose tissue
12011658 Diabetes mellitus, type II
Obesity
Insulin resistance
2,051
16427 Ramipril decreases_activity of ACE
11597291 Diabetes mellitus, type II
Insulin resistance
2,056
16437 ACE increases_quantity of Angiotensin II
16438 ACE decreases_quantity of Angiotensin I
16439 ACE increases_quantity of His-Leu
16593 ACE is_expressed_in epithelial cell
16595 ACE decreases_quantity of Bradykinin
16597 ACE increases_quantity of Phe-Arg
16598 ACE affects_activity of enkephalin metabolic process
16600 ACE decreases_quantity of Met-enkephalin heptapeptide
16603 ACE decreases_quantity of Met-enkephalin
16604 ACE increases_quantity of Phe-Met
16606 ACE increases_quantity of Tyr-Gly-Gly
16613 ACE increases_quantity of Met-enkephalin
16614 ACE increases_quantity of Arg-Phe
16615 ACE decreases_quantity of Met-enkephalin octapeptide
16616 ACE increases_quantity of Gly-Leu
16617 ACE increases_quantity of Met-Arg
16618 ACE increases_quantity of Tyr-Gly-Gly-Phe
16619 ACE decreases_quantity of Neurotensin (1-13)
16620 ACE increases_quantity of Leucine/Isoleucine
16621 ACE decreases_quantity of des-Arg9-bradykinin
16622 ACE increases_quantity of Ser-Pro-Phe
16623 ACE decreases_quantity of fMet-Leu-Phe
16624 ACE increases_quantity of Leu-Phe
16625 ACE decreases_quantity of Substance P
16627 ACE increases_quantity of Gly-Leu-Met-NH2
16628 ACE increases_quantity of Leu-Met-NH2
16629 Captopril decreases_activity of ACE
16630 ACE decreases_quantity of Gonadoliberin-1
16634 ACE increases_quantity of Arg-Pro-Gly-NH2
16635 ACE increases_quantity of Glu-His-Trp
16646 His-Leu decreases_activity of ACE
16647 Phe-Arg decreases_activity of ACE
16648 Insulin B chain decreases_activity of ACE
46090 ACE is_expressed_in neuroepithelium
46091 ACE is_expressed_in testis
46092 ACE is_expressed_in prostate gland
46093 ACE is_expressed_in epididymis
46094 ACE is_expressed_in seminal plasma
2440624 Diabetes mellitus, type II
Insulin resistance
2,069
16661 ACE decreases_quantity of AcSDKP
16662 ACE increases_quantity of Lys-Pro
16734 ACE increases_quantity of Ac-Ser-Asp
7876104 Diabetes mellitus, type II
Insulin resistance
2,074
16725 ACE decreases_quantity of Beta-neoendorphin(1-9)
16726 ACE increases_quantity of Beta-neoendorphin(1-7)
16727 ACE increases_quantity of Tyr-Pro
16728 ACE decreases_quantity of Beta-neoendorphin(1-7)
16729 ACE increases_quantity of Leu-enkephalin
16730 ACE increases_quantity of Arg-Lys
16731 ACE decreases_quantity of Leu-enkephalin
16732 ACE increases_quantity of Tyr-Gly-Gly
16733 ACE increases_quantity of Phe-Leu
9165097 Diabetes mellitus, type II
Insulin resistance
2,075
16735 ACE decreases_quantity of Cholecystokinin-8
16736 ACE increases_quantity of Asp-Phe-NH2
16737 ACE increases_quantity of Trp-Met
16738 ACE increases_quantity of Gly-Trp-Met
2554881 Diabetes mellitus, type II
Insulin resistance
2,076
16739 ACE decreases_quantity of Alpha-MSH
16740 ACE decreases_quantity of ACTH
17363457 Diabetes mellitus, type II
Insulin resistance
2,077
16743 ACE decreases_quantity of Gonadoliberin-1
16744 ACE increases_quantity of Arg-Pro-Gly-NH2
16745 ACE increases_quantity of Glu-His-Trp
16746 ACE increases_quantity of Gly-Leu
16747 ACE increases_quantity of Ser-Tyr
2983326 Diabetes mellitus, type II
Insulin resistance
2,098
17034 Perindopril decreases_activity of ACE in brain
17039 Enalapril decreases_activity of ACE
17040 Imidapril decreases_activity of ACE
20627092 Alzheimer disease
2,172
18186 Obesity NOT affects_expression of ACE in lung, in epididymal adipose tissue, retroperitoneal adipose tissue, in subcutaneous adipose tissue
15191907 Diabetes mellitus, type II
Obesity
Insulin resistance
2,212
18583 Alzheimer disease increases_quantity of ACE in the cerebrospinal fluid (CSF) of patients with mild cognitive impairment and AD
18600 27-Hydroxycholesterol affects_activity of ACE in plasma and the cerebrospinal fluid (CSF)
18608 ACE increases_activity of brain renin-angiotensin system in AD brain
21297254 Alzheimer disease
Endocrine
2,619
24858 ACE affects_activity of Alzheimer disease
21955788 Alzheimer disease
3,828
38320 ACE affects_activity of bradykinin catabolic process in blood serum
38324 sex affects_activity of ACE in blood serum
11406494 Diabetes mellitus, type II
Insulin resistance
3,951
40111 Genistein decreases_activity of ACE in blood plasma
19233159 Diabetes mellitus, type II
Insulin resistance
5,015
49512 OLR1 increases_expression of ACE
49515 OLR1 increases_quantity of ACE
12504834 Cardiovascular disease
Atherosclerosis
7,302
71733 ACE affects_quantity of ICAM1 via hypermethylation of a CpG island in the proximal ACE promoter
71734 ACE affects_quantity of SELE via hypermethylation of a CpG island in the proximal ACE promoter
71735 ACE affects_quantity of SELP via hypermethylation of a CpG island in the proximal ACE promoter
22808171 Cardiovascular disease
Major depressive disorder
7,511
74118 AHR affects_expression of ACE
20878756 Diabetes mellitus, type II
Insulin resistance
Inflammatory bowel disease
7,731
77314 Diabetes mellitus, type I increases_activity of ACE in blood plasma
26971351 Diabetes mellitus, type II
Insulin resistance
Cardiovascular disease
Chronic kidney disease
8,563
88222 low-copper diet increases_expression of ACE
88223 high-sucrose diet increases_expression of ACE
26033743 Diabetes mellitus, type II
Insulin resistance
Fatty liver disease, nonalcoholic
9,551
101281 VAV2 affects_quantity of ACE
17202406 Cardiovascular disease
11,684
116061 sex affects_activity of ACE in cardiac tissue
116068 Testosterone increases_activity of ACE in cardiac tissue
117240 sex, male increases_activity of ACE in cardiac tissue; compared to female
Cardiovascular disease
COVID-19
11,717
116173 Obesity increases_expression of ACE in pancreas
116319 ACE decreases_quantity of Angiotensin I
116323 ACE increases_quantity of Angiotensin II
116432 TNFRSF11B increases_expression of ACE
30404071 Diabetes mellitus, type II
Insulin resistance
11,748
116362 ACE increases_quantity of Angiotensin II
116363 ACE decreases_quantity of Angiotensin I
32333398 COVID-19
11,751
117231 ACE decreases_quantity of Angiotensin I
15283675 Endocrine
11,756
116636 ACE increases_activity of lung injury
32333398 COVID-19
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