|
98
|
| 319 |
SOD1-p.G93A
|
|
increases_activity of
|
microglial cell activation
|
in microglia cultures
|
| 320 |
SOD1-p.G85R
|
|
increases_activity of
|
microglial cell activation
|
in microglia cultures
|
| 334 |
CD14
|
|
affects_activity of
|
microglial cell activation
|
induced by extracellular mSOD1(G93A)
|
| 335 |
TLR2
|
|
affects_activity of
|
microglial cell activation
|
induced by extracellular mSOD1(G93A)
|
| 336 |
TLR4
|
|
affects_activity of
|
microglial cell activation
|
induced by extracellular mSOD1(G93A)
|
|
19672969
|
Amyotrophic lateral sclerosis
|
|
177
|
| 720 |
SOD1-p.G93A
|
|
increases_activity of
|
microglial cell activation
|
between stage P28 and P32
|
| 750 |
CNTF
|
|
decreases_activity of
|
microglial cell activation
|
in mutant SOD1(G93A) fast-mice
|
| 771 |
Salubrinal
|
|
decreases_activity of
|
microglial cell activation
|
in mutant SOD1(G93A) fast-mice
|
|
19330001
|
Amyotrophic lateral sclerosis
|
|
379
|
| 1551 |
Lipophilic metal chelator DP-109
|
|
decreases_activity of
|
microglial cell activation
|
in SOD1(G93A) transgenic mice
|
|
17630988
|
Amyotrophic lateral sclerosis
|
|
404
|
| 1767 |
SOD1-p.G93A
|
|
increases_activity of
|
microglial cell activation
|
in SOD1G93A transgenic mice
|
|
19734218
|
Amyotrophic lateral sclerosis
|
|
410
|
| 1776 |
Amyotrophic lateral sclerosis
|
|
increases_activity of
|
microglial cell activation
|
|
| 1782 |
Multiple sclerosis
|
|
increases_activity of
|
microglial cell activation
|
|
|
16512913
|
Multiple sclerosis
Amyotrophic lateral sclerosis
|
|
547
|
| 13802 |
EPO
|
|
decreases_activity of
|
microglial cell activation
|
in pilocarpine model
|
|
18479396
|
Status epilepticus
|
|
1,071
|
| 7434 |
PROC-mut
|
|
decreases_activity of
|
microglial cell activation
|
|
|
19841542
|
Amyotrophic lateral sclerosis
|
|
1,100
|
| 6986 |
Parkinson disease
|
|
cooccurs with
|
microglial cell activation
|
in substantia nigra
|
| 6987 |
microglial cell activation
|
|
increases_activity of
|
neuron death
|
in substantia nigra
|
| 6988 |
microglial cell activation
|
|
increases_activity of
|
response to oxidative stress
|
|
| 6989 |
microglial cell activation
|
|
increases_quantity of
|
Proinflammatory cytokine
|
|
|
20423606
|
Parkinson disease
|
|
1,103
|
| 7000 |
F2
|
|
increases_activity of
|
microglial cell activation
|
|
|
20025058
|
Parkinson disease
|
|
1,105
|
| 7012 |
microglial cell activation
|
|
increases_quantity of
|
NOS2
|
|
| 7014 |
microglial cell activation
|
|
increases_quantity of
|
PTGS2
|
|
| 7015 |
microglial cell activation
|
|
increases_quantity of
|
IL1B
|
|
| 7017 |
microglial cell activation
|
|
increases_quantity of
|
IL6
|
|
| 7018 |
microglial cell activation
|
|
increases_quantity of
|
TNF
|
|
| 7019 |
microglial cell activation
|
|
increases_activity of
|
neuron death
|
in substantia nigra
|
| 7021 |
Parkinson disease
|
|
cooccurs with
|
microglial cell activation
|
in substantia nigra
|
| 7024 |
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
|
|
increases_activity of
|
microglial cell activation
|
in substantia nigra
|
| 7027 |
6-OHDA
|
|
increases_activity of
|
microglial cell activation
|
in substantia nigra
|
|
20025058
|
Parkinson disease
|
|
1,111
|
| 7191 |
Alzheimer disease
|
|
increases_activity of
|
microglial cell activation
|
|
|
11329064
|
Alzheimer disease
|
|
1,112
|
| 7183 |
transgenic hAPP/TGFbeta1 mouse
|
|
increases_activity of
|
microglial cell activation
|
in transgenic hAPP/TGF-beta1 mice
|
| 7194 |
TGFB1
|
|
increases_activity of
|
microglial cell activation
|
in brain; of transgenic hAPP/TGF-beta1 mice
|
|
11329064
|
Alzheimer disease
|
|
1,115
|
| 7166 |
NaHS
|
|
decreases_activity of
|
microglial cell activation
|
in substantia nigra
|
|
20041858
|
Parkinson disease
|
|
1,116
|
| 7197 |
SNCA
|
|
increases_activity of
|
microglial cell activation
|
in substantia nigra
|
| 7199 |
alpha-synuclein inclusion body
|
|
increases_activity of
|
microglial cell activation
|
in substantia nigra
|
|
20098715
|
Parkinson disease
|
|
1,124
|
| 8760 |
NR4A2
|
|
decreases_activity of
|
microglial cell activation
|
|
|
19345186
|
Parkinson disease
|
|
1,126
|
| 7313 |
SNCA-p.A53T
|
|
increases_activity of
|
microglial cell activation
|
in striatum, but not in substantia nigra
|
|
19295143
|
Parkinson disease
|
|
1,127
|
| 7320 |
Lipopolysaccharide
|
|
increases_activity of
|
microglial cell activation
|
|
|
18686098
|
Parkinson disease
|
|
1,133
|
| 7369 |
convulsive seizures
|
|
affects_activity of
|
microglial cell activation
|
|
|
19845729
|
Epilepsy, temporal lobe
|
|
1,137
|
| 7399 |
SNCA
|
|
increases_activity of
|
microglial cell activation
|
|
| 7446 |
F2R
|
|
affects_activity of
|
microglial cell activation
|
in microglia; induced by alpha-synuclein
|
| 11692 |
alpha-synuclein inclusion body
|
|
increases_activity of
|
microglial cell activation
|
|
|
20511551
|
Parkinson disease
|
|
1,145
|
| 7457 |
SNCA
|
|
increases_activity of
|
microglial cell activation
|
|
| 7460 |
SNCA-p.A30P
|
|
increases_activity of
|
microglial cell activation
|
more efficiently than wildtype SNCA
|
| 7462 |
SNCA-p.E46K
|
|
increases_activity of
|
microglial cell activation
|
more efficiently than wildtype SNCA
|
| 7463 |
SNCA-p.A53T
|
|
increases_activity of
|
microglial cell activation
|
more efficiently than wildtype SNCA
|
|
17166628
|
Parkinson disease
|
|
1,184
|
| 7845 |
microglial cell activation
|
|
increases_activity of
|
inflammatory response
|
within the diseased brain
|
| 7865 |
microglial cell activation
|
|
increases_quantity of
|
Peroxynitrite
|
|
|
17094809
|
Alzheimer disease
Chronic granulomatous disease
|
|
1,199
|
| 8014 |
microglial cell activation
|
|
increases_activity of
|
Parkinson disease
|
|
|
15791003
|
Parkinson disease
|
|
1,200
|
| 8016 |
alpha-synuclein inclusion body
|
|
increases_activity of
|
microglial cell activation
|
|
|
15791003
|
Dementia, Lewy body
Parkinson disease
|
|
1,204
|
| 8088 |
SNCA-p.A53T
|
|
increases_activity of
|
microglial cell activation
|
|
| 8091 |
microglial cell activation
|
|
increases_activity of
|
neuron death
|
|
|
20409326
|
Parkinson disease
|
|
1,215
|
| 8161 |
microglial cell activation
|
|
increases_activity of
|
innate immune response
|
in brain
|
| 8162 |
microglial cell activation
|
|
increases_quantity of
|
Reactive oxygen species
|
in brain
|
| 8163 |
microglial cell activation
|
|
increases_quantity of
|
TNF
|
in brain
|
| 8164 |
microglial cell activation
|
|
increases_quantity of
|
IL1B
|
in brain
|
| 8165 |
microglial cell activation
|
|
increases_activity of
|
inflammatory response
|
in brain
|
| 8173 |
SNCA
|
|
increases_activity of
|
microglial cell activation
|
|
| 8185 |
microglial cell activation
|
|
increases_quantity of
|
IL1B
|
|
| 8186 |
microglial cell activation
|
|
increases_quantity of
|
IL6
|
|
| 8187 |
microglial cell activation
|
|
increases_quantity of
|
PTGS2
|
|
| 8188 |
microglial cell activation
|
|
increases_quantity of
|
NOS2
|
|
|
17537546
|
Parkinson disease
|
|
1,218
|
| 8180 |
SNCA
|
|
increases_activity of
|
microglial cell activation
|
in substantia nigra
|
| 8183 |
TNF
|
|
increases_activity of
|
microglial cell activation
|
|
| 8198 |
CD36
|
|
affects_activity of
|
microglial cell activation
|
via SNCA
|
|
17537546
|
Parkinson disease
|
|
1,227
|
| 8248 |
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
|
|
increases_activity of
|
microglial cell activation
|
in striatum and substantia nigra
|
|
15163680
|
Parkinson disease
|
|
1,236
|
| 8547 |
SNCA
|
|
increases_activity of
|
microglial cell activation
|
if SNCA is in a protofibrillar structure
|
|
20074453
|
Parkinson disease
|
|
1,242
|
| 8379 |
microglial cell activation
|
|
increases_activity of
|
phagocytosis
|
in brain
|
| 8385 |
SNCA
|
|
increases_activity of
|
microglial cell activation
|
in brain
|
|
18449945
|
Parkinson disease
|
|
1,249
|
| 8454 |
microglial cell activation
|
|
increases_quantity of
|
NO
|
|
|
11517237
|
Parkinson disease
|
CIDeRplus