|
304
|
| 1214 |
VEGFA
|
|
increases_activity of
|
learning or memory
|
|
| 1215 |
PGF
|
|
decreases_activity of
|
learning or memory
|
|
| 1216 |
KDR
|
|
affects_activity of
|
learning or memory
|
|
|
15258583
|
Amyotrophic lateral sclerosis
|
|
457
|
| 2114 |
Streptozocin
|
|
decreases_activity of
|
learning or memory
|
|
|
19712582
|
Alzheimer disease
|
|
487
|
| 2299 |
Insulin
|
|
affects_activity of
|
learning or memory
|
|
| 2303 |
Glucose
|
|
affects_activity of
|
learning or memory
|
|
| 2304 |
Alzheimer disease
|
|
decreases_activity of
|
learning or memory
|
|
|
15094077
|
Alzheimer disease
|
|
497
|
| 2419 |
EGb761 (antidementive drug)
|
|
increases_activity of
|
learning or memory
|
|
|
10672254
|
Alzheimer disease
|
|
571
|
| 2990 |
Lipoate
|
|
increases_activity of
|
learning or memory
|
in pilocarpine model
|
|
19669875
|
Status epilepticus
|
|
586
|
| 3091 |
CRMP1
|
|
affects_activity of
|
learning or memory
|
|
|
17344389
|
Amyotrophic lateral sclerosis
|
|
593
|
| 3120 |
DLG4
|
|
affects_activity of
|
learning or memory
|
|
|
9853749
|
Amyotrophic lateral sclerosis
|
|
652
|
| 3456 |
PS1/PS2 KO mouse
|
|
decreases_activity of
|
learning or memory
|
in the forebrain of mice
|
| 3470 |
PSEN1-mut
|
|
affects_activity of
|
learning or memory
|
in the forebrain of mice
|
| 3472 |
PSEN2-mut
|
|
affects_activity of
|
learning or memory
|
in the forebrain of mice
|
|
18189321
|
Alzheimer disease
|
|
658
|
| 3524 |
Alzheimer disease
|
|
decreases_activity of
|
learning or memory
|
|
|
19337449
|
Alzheimer disease
|
|
873
|
| 5156 |
NOS1 rs6490121
|
|
affects_activity of
|
learning or memory
|
|
| 5157 |
NOS1 rs6490121
|
|
affects_activity of
|
learning or memory
|
|
|
19805695
|
Schizophrenia
|
|
998
|
| 6195 |
Ginkgo biloba
|
|
increases_activity of
|
learning or memory
|
compared to female wild-type mice
|
|
14637120
|
Alzheimer disease
|
|
1,057
|
| 6603 |
PS cDKO mouse
|
|
affects_activity of
|
learning or memory
|
|
|
15345711
|
Alzheimer disease
|
|
1,377
|
| 9709 |
response to hypoxia
|
|
decreases_activity of
|
learning or memory
|
|
|
20552043
|
Alzheimer disease
|
|
1,588
|
| 11761 |
Alzheimer disease
|
|
decreases_activity of
|
learning or memory
|
|
|
20463396
|
Alzheimer disease
Multiple sclerosis
Parkinson disease
|
|
1,659
|
| 12273 |
CLCN3-mut
|
|
affects_activity of
|
learning or memory
|
|
|
12196559
|
Alzheimer disease
|
|
1,870
|
| 14197 |
TTBK1-Tg mouse
|
|
affects_activity of
|
learning or memory
|
|
|
19118186
|
Alzheimer disease
|
|
1,893
|
| 14521 |
APOE (isoform E4)
|
|
decreases_activity of
|
learning or memory
|
compared to apo E3 knock-in mice
|
|
20170744
|
Alzheimer disease
|
|
1,935
|
| 14876 |
Amyloid beta peptide (40)
|
|
decreases_activity of
|
learning or memory
|
|
| 14877 |
Amyloid beta peptide (42)
|
|
decreases_activity of
|
learning or memory
|
|
| 14963 |
long-term synaptic potentiation
|
|
affects_activity of
|
learning or memory
|
|
| 15054 |
Amyloid beta peptide
|
|
decreases_activity of
|
learning or memory
|
in entorhinal and frontal cortices; of Alzheimer disease patients
|
|
16025111
|
Alzheimer disease
|
|
1,957
|
| 15529 |
decreased oxoglutarate dehydrogenase activity
|
|
decreases_activity of
|
learning or memory
|
in the emotional domain
|
|
19076444
|
Alzheimer disease
|
|
1,974
|
| 15474 |
VIP
|
|
affects_activity of
|
learning or memory
|
|
| 15475 |
VIPR1
|
|
affects_activity of
|
learning or memory
|
|
| 15476 |
VIPR2
|
|
affects_activity of
|
learning or memory
|
|
|
18616823
|
Neurological
Schizophrenia
|
|
2,072
|
| 38965 |
APOE (isoform E4)
|
|
decreases_activity of
|
learning or memory
|
in APOE4 mice; if mice are fed with selective mitochondrial antioxidants acetyl-L-carnitine and R-alpha-lipoic acid
|
|
19342064
|
Alzheimer disease
|
|
2,098
|
| 17041 |
Abeta (25‚Äď35) injected mouse
|
|
decreases_activity of
|
learning or memory
|
|
| 17241 |
Perindopril
|
|
increases_activity of
|
learning or memory
|
|
| 17243 |
Enalapril
|
NOT |
increases_activity of
|
learning or memory
|
|
| 17244 |
Imidapril
|
NOT |
increases_activity of
|
learning or memory
|
|
|
20627092
|
Alzheimer disease
|
|
2,337
|
| 20366 |
Rosiglitazone
|
|
increases_activity of
|
learning or memory
|
in Tg2576 mice
|
| 20372 |
Metyrapone
|
|
increases_activity of
|
learning or memory
|
in Tg2576 mice
|
|
16515786
|
Alzheimer disease
|
|
3,082
|
| 28304 |
Insulin
|
|
affects_activity of
|
learning or memory
|
after intrahippocampal insulin microinjection, dose-dependent
|
|
16890939
|
Diabetes mellitus, type II
Insulin resistance
|
|
3,335
|
| 30624 |
increased cortisol level
|
NOT |
affects_activity of
|
learning or memory
|
Salivary cortisol was measured; in the AD group
|
|
20157240
|
Alzheimer disease
|
|
3,366
|
| 30910 |
Corticosterone
|
|
decreases_activity of
|
learning or memory
|
|
|
18278039
|
Diabetes mellitus, type II
Insulin resistance
|
|
3,367
|
| 30903 |
Streptozocin
|
|
decreases_activity of
|
learning or memory
|
|
| 30904 |
Corticosterone
|
|
decreases_activity of
|
learning or memory
|
|
|
18278039
|
Diabetes mellitus, type II
Diabetes mellitus, type I
Insulin resistance
|
|
3,440
|
| 32002 |
exercise
|
|
increases_activity of
|
learning or memory
|
in APP transgenic mice with HFD (high fat diet) induced beta-amyloid deposition
|
| 32012 |
exercise
|
|
decreases_activity of
|
learning or memory
|
in APP transgenic mice with HFD (high fat diet) induced beta-amyloid deposition
|
|
22563077
|
Alzheimer disease
|
|
3,466
|
| 32282 |
TOB1
|
|
increases_activity of
|
learning or memory
|
|
|
15730870
|
Mental
|
|
3,502
|
| 32638 |
increased cortisol level
|
|
decreases_activity of
|
learning or memory
|
in old age
|
|
16125145
|
Alzheimer disease
|
CIDeRplus