|
1,163
|
| 7642 |
Lipopolysaccharide
|
NOT |
affects_activity of
|
innate immune response
|
in mutant SOD1G37R mice; after a single systemic LPS injection
|
| 7652 |
Lipopolysaccharide
|
|
affects_activity of
|
innate immune response
|
in mutant SOD1G37R mice; after chronic systemic injections of an equal dose LPS
|
|
14960605
|
Amyotrophic lateral sclerosis
|
|
1,184
|
| 7855 |
microglia
|
|
increases_activity of
|
innate immune response
|
in brain; they are the resident innate immune cells
|
| 7856 |
Amyloid beta peptide (fibrillar)
|
|
increases_activity of
|
innate immune response
|
|
|
17094809
|
Alzheimer disease
Chronic granulomatous disease
|
|
1,215
|
| 8160 |
astrocyte activation
|
|
increases_activity of
|
innate immune response
|
in brain
|
| 8161 |
microglial cell activation
|
|
increases_activity of
|
innate immune response
|
in brain
|
|
17537546
|
Parkinson disease
|
|
1,588
|
| 11452 |
innate immune response
|
|
affects_activity of
|
Cytokine
|
|
| 11453 |
response to stress
|
|
affects_activity of
|
innate immune response
|
|
| 11454 |
innate immune response
|
|
affects_activity of
|
inflammatory response
|
|
| 11456 |
innate immune response
|
|
increases_quantity of
|
Reactive oxygen species
|
|
| 11457 |
innate immune response
|
|
increases_quantity of
|
NO
|
|
| 11458 |
innate immune response
|
|
affects_activity of
|
central nervous system myelination
|
exactly: remyelination
|
| 11459 |
microglia
|
|
increases_activity of
|
innate immune response
|
|
|
20463396
|
Alzheimer disease
Multiple sclerosis
Parkinson disease
|
|
3,658
|
| 34853 |
natural killer cell
|
|
affects_activity of
|
innate immune response
|
|
|
22871633
|
Multiple sclerosis
|
|
4,118
|
| 42501 |
Melanocortin
|
|
decreases_activity of
|
innate immune response
|
of e.g. macrophages peripherally and microglia in the CNS
|
|
23034287
|
Multiple sclerosis
|
|
6,660
|
| 64509 |
Glucosylceramide
|
|
affects_activity of
|
innate immune response
|
|
|
26108617
|
Diabetes mellitus, type II
Insulin resistance
|
|
6,822
|
| 66385 |
MUC19
|
|
increases_activity of
|
innate immune response
|
|
|
25512380
|
Inflammation
|
|
6,845
|
| 66617 |
ARPC1A
|
|
increases_activity of
|
innate immune response
|
|
| 67910 |
EXOC2
|
|
affects_activity of
|
innate immune response
|
|
|
20570966
|
Inflammatory bowel disease
|
|
6,925
|
| 67672 |
NOD2
|
|
affects_activity of
|
innate immune response
|
|
|
21677747
|
Inflammatory bowel disease 1
Inflammatory bowel disease
|
|
6,952
|
| 67946 |
CARD9
|
|
affects_activity of
|
innate immune response
|
|
|
27158904
|
Gastrointestinal
Inflammatory bowel disease
Inflammation
|
|
6,953
|
| 67956 |
CARD9
|
|
affects_activity of
|
innate immune response
|
|
|
17187069
|
Inflammation
|
|
6,991
|
| 68577 |
TRAF4
|
|
decreases_activity of
|
innate immune response
|
after phosphorylation by CHUK
|
|
22547678
|
Inflammation
|
|
7,082
|
| 69665 |
LUBAC complex
|
|
affects_activity of
|
innate immune response
|
|
|
|
Inflammation
|
|
7,526
|
| 75828 |
gut microbiota
|
|
affects_activity of
|
innate immune response
|
|
|
25073467
|
Gastrointestinal
Metabolic
|
|
7,534
|
| 74398 |
CRP
|
|
increases_activity of
|
innate immune response
|
|
|
23114023
|
Immunological
Cardiovascular disease
Atherosclerosis
|
|
7,535
|
| 74412 |
CRP-LPC complex
|
NOT |
increases_activity of
|
innate immune response
|
in 293FT cells
|
| 74413 |
Lysophosphatidylcholine
|
NOT |
increases_activity of
|
innate immune response
|
in 293FT cells; if LPC is complexed with CRP
|
|
23114023
|
Cardiovascular disease
Atherosclerosis
|
|
7,758
|
| 79079 |
mast cell
|
|
affects_activity of
|
innate immune response
|
|
|
26779180
|
Immunological
Inflammation
|
|
7,859
|
| 78334 |
FADD
|
|
affects_activity of
|
innate immune response
|
|
| 78350 |
RIPK1
|
|
affects_activity of
|
innate immune response
|
|
|
24204270
|
Immunological
|
|
7,861
|
| 78352 |
RIG-I signaling pathway
|
|
increases_activity of
|
innate immune response
|
|
|
24204270
|
Immunological
|
|
7,975
|
| 79085 |
TRAF3
|
|
affects_activity of
|
innate immune response
|
|
|
22131337
|
Immunological
Inflammation
|
|
8,052
|
| 79712 |
IFITM1
|
|
affects_activity of
|
innate immune response
|
|
| 79713 |
IFITM2
|
|
affects_activity of
|
innate immune response
|
|
| 79714 |
IFITM3
|
|
affects_activity of
|
innate immune response
|
|
|
20064371
|
Immunological
|
|
9,140
|
| 97640 |
gut microbiota
|
|
increases_activity of
|
innate immune response
|
in the host
|
|
30441866
|
Neurological
Alzheimer disease
Gastrointestinal
Metabolic
|
|
9,235
|
| 98260 |
mir-155
|
|
affects_activity of
|
innate immune response
|
|
|
30577275
|
Metabolic
Inflammation
|
|
10,777
|
| 110057 |
mitochondria-associated endoplasmic reticulum membrane
|
|
increases_activity of
|
innate immune response
|
perhaps ApoE4 mitigates infectivity
|
|
26564908
|
Alzheimer disease
Metabolic
|
|
10,846
|
| 110444 |
PANX3
|
|
increases_activity of
|
innate immune response
|
|
|
27506198
|
Immunological
Metabolic
|
|
10,861
|
| 110648 |
PDE12
|
|
decreases_activity of
|
innate immune response
|
due to lowering the amount of 2',5'-linked adenylate polymers
|
|
26055709
|
Immunological
Inflammation
|
|
10,943
|
| 111376 |
DDX58
|
|
increases_activity of
|
innate immune response
|
|
| 111379 |
G3BP1
|
|
increases_activity of
|
innate immune response
|
by binding to RIG-I (DDX58)
|
|
30804210
|
Immunological
Inflammation
|
|
11,022
|
| 111869 |
microglia
|
|
increases_activity of
|
innate immune response
|
in CNS; microglia are the resident innate immune cells
|
|
30038567
|
Alzheimer disease
|
|
11,023
|
| 111890 |
innate immune response
|
|
increases_activity of
|
phagocytosis
|
chemotaxis and phagocytosis are two crucial innate immune functions
|
| 112194 |
innate immune response
|
|
increases_activity of
|
chemotaxis
|
chemotaxis and phagocytosis are two crucial innate immune functions
|
|
27239545
|
Alzheimer disease
|
CIDeRplus