|
6,285
|
| 58824 |
TRPC4AP
|
|
increases_activity of
|
calcium ion import
|
into the endoplasmic reticulum; in the presence of TNF-R1 and TRPC4
|
|
20458742
|
Metabolic
|
|
6,632
|
| 63383 |
Lithium
|
|
decreases_activity of
|
calcium ion import
|
mediated by the NMDA receptor
|
| 63385 |
GRIN2B
|
|
increases_activity of
|
calcium ion import
|
|
| 63388 |
NMDA receptor complex
|
|
increases_activity of
|
calcium ion import
|
|
|
11841566
|
Neurological
|
|
7,027
|
| 68803 |
ALMS1
|
|
increases_activity of
|
calcium ion import
|
in kidney epithelium
|
|
|
Diabetes mellitus, type II
Insulin resistance
Alstrom syndrome
Ciliopathy
|
|
7,257
|
| 71422 |
SYPL2
|
|
affects_activity of
|
calcium ion import
|
into the sarcoplasmic reticulum
|
|
15538969
|
Diabetes mellitus, type II
Insulin resistance
|
|
7,261
|
| 71381 |
TRPC4
|
|
affects_activity of
|
calcium ion import
|
|
|
|
Metabolic
|
|
7,262
|
| 71453 |
Lysophosphatidylcholine
|
|
increases_activity of
|
calcium ion import
|
in ventricular myocytes
|
|
|
Cardiovascular
|
|
7,266
|
| 71428 |
TRPC4 rs73184536
|
|
increases_activity of
|
calcium ion import
|
in HEK293 cells
|
| 71434 |
TRPC4
|
|
affects_activity of
|
calcium ion import
|
in HEK293 cells
|
| 71437 |
calcium ion import
|
|
increases_activity of
|
relaxation of vascular smooth muscle
|
|
|
|
Myocardial infarction
|
|
7,269
|
| 71442 |
TRPC4
|
|
increases_activity of
|
calcium ion import
|
|
|
|
Cardiovascular
|
|
7,531
|
| 75108 |
Voltage-gated calcium channel
|
|
increases_activity of
|
calcium ion import
|
in pancreatic beta cells
|
| 75109 |
calcium ion import
|
|
increases_activity of
|
release of sequestered calcium ion into cytosol by endoplasmic reticulum
|
in pancreatic beta cells; in the presence of cAMP elevating reagents such as GLP1 or GIP
|
| 75114 |
calcium ion import
|
|
increases_activity of
|
increased intracellular calcium level
|
in pancreatic beta cells
|
| 75126 |
Voltage-gated calcium channel, L-type
|
|
increases_activity of
|
calcium ion import
|
in pancreatic alpha cells
|
| 75127 |
Voltage-gated calcium channel, N-type
|
|
increases_activity of
|
calcium ion import
|
in pancreatic alpha cells
|
| 75128 |
Voltage-gated calcium channel, T-type
|
|
increases_activity of
|
calcium ion import
|
in pancreatic alpha cells
|
| 75129 |
Voltage-gated calcium channel, R-type
|
|
increases_activity of
|
calcium ion import
|
in pancreatic alpha cells
|
| 75232 |
calcium ion import
|
|
increases_activity of
|
somatostatin secretion
|
|
|
28275047
|
Diabetes mellitus, type II
Insulin resistance
|
|
8,021
|
| 79822 |
Protein kinase A
|
|
increases_activity of
|
calcium ion import
|
|
| 79823 |
RAPGEF4
|
|
increases_activity of
|
calcium ion import
|
|
|
25834231
|
Diabetes mellitus, type II
Insulin resistance
|
|
8,208
|
| 83120 |
Indole
|
|
increases_activity of
|
calcium ion import
|
|
|
25456122
|
Diabetes mellitus, type II
Insulin resistance
|
|
8,588
|
| 88508 |
Amyloid beta peptide (42, oligomer)
|
|
increases_activity of
|
calcium ion import
|
intracellular in rat cortical neurons in culture and entorhinal-hippocampal organotypic slices; requiring NMDA and AMPA receptor activation
|
| 88509 |
NMDA receptor complex
|
|
increases_activity of
|
calcium ion import
|
into mitochondria; induced by Abeta oligomers, increasing mitochondrial dysfunction
|
| 88516 |
AMPA receptor complex
|
|
increases_activity of
|
calcium ion import
|
into mitochondria; induced by Abeta oligomers, increasing mitochondrial dysfunction
|
|
20061018
|
Neurological
Alzheimer disease
|
|
8,790
|
| 91776 |
Phosphate
|
|
decreases_activity of
|
calcium ion import
|
into the sarcoplasmic reticulum
|
|
11821531
|
Metabolic
|
|
9,001
|
| 94372 |
APOE (isoform E4)
|
|
decreases_activity of
|
calcium ion import
|
concerning Reelin-induced NMDA receptor-mediated Ca2+ influx
|
|
20547867
|
Alzheimer disease
|
|
9,072
|
| 95013 |
ADORA1
|
|
decreases_activity of
|
calcium ion import
|
pre-synaptic
|
|
27365148
|
Parkinson disease
Major depressive disorder
|
|
9,122
|
| 96992 |
ATP
|
|
decreases_activity of
|
calcium ion import
|
in brown adipose tissue
|
|
29619754
|
Diabetes mellitus, type II
Obesity
Insulin resistance
|
|
11,191
|
| 113034 |
CHRNA7
|
|
increases_activity of
|
calcium ion import
|
|
|
25701707
|
Chromosome 15q13.3 deletion syndrome
|
|
11,300
|
| 113520 |
decreased MFN2 level
|
|
decreases_activity of
|
calcium ion import
|
in mitochondria without MFN2; upon IP3R activation
|
| 115526 |
MFN2
|
|
increases_activity of
|
calcium ion import
|
in mitochondria without MFN2 the Ca2+ uptake is decreased
|
|
30590907
|
Alzheimer disease
Metabolic
|
|
11,426
|
| 114171 |
SYK
|
|
decreases_activity of
|
calcium ion import
|
into endoplasmic reticulum
|
|
29601906
|
Diabetes mellitus, type II
Insulin resistance
Cardiomyopathy, diabetic
|
|
11,492
|
| 114703 |
calcium-mediated signaling using extracellular calcium source
|
|
increases_activity of
|
calcium ion import
|
into cell
|
|
18478527
|
Alzheimer disease
|
|
12,104
|
| 149144 |
APOE (isoform E4)
|
|
increases_activity of
|
calcium ion import
|
into the damaged neurons; APOE triggers Ca2+ overload through NMDAR and CaMK II signaling pathway
|
|
29272008
|
Neurological
Alzheimer disease
|
|
12,511
|
| 121794 |
increased ATP/ADP ratio
|
|
increases_activity of
|
calcium ion import
|
in pancreatic beta cells
|
|
28202288
|
Diabetes mellitus, type II
Insulin resistance
|
|
13,390
|
| 126170 |
PKD2
|
|
increases_activity of
|
calcium ion import
|
|
|
12514735
|
Ciliopathy
|
|
13,839
|
| 130098 |
Ion channel, mechanosensitive
|
|
increases_activity of
|
calcium ion import
|
|
| 130101 |
calcium ion import
|
|
increases_activity of
|
ERK1 and ERK2 cascade
|
|
| 130108 |
cilium
|
|
increases_activity of
|
calcium ion import
|
|
|
24352503
|
Chronic kidney disease
|
|
13,918
|
| 131464 |
membrane depolarization
|
|
increases_activity of
|
calcium ion import
|
in pancreatic beta cells
|
| 131465 |
calcium ion import
|
|
increases_activity of
|
increased cytosolic calcium level
|
in pancreatic beta cells
|
|
16249427
|
Diabetes mellitus, type II
Insulin resistance
|
|
13,919
|
| 131498 |
Voltage-gated calcium channel
|
|
increases_activity of
|
calcium ion import
|
in pancreatic beta cells
|
| 131499 |
calcium ion import
|
|
increases_activity of
|
increased cytosolic calcium level
|
in pancreatic beta cells
|
|
32935446
|
MODY, type XIII
|
|
14,128
|
| 133502 |
NMDA receptor complex
|
|
increases_activity of
|
calcium ion import
|
in adult rat hippocampal slice; likely through the receptor ion channel complex, as well as release of calcium from the mitochondria through activation of the 2Na(+)-Ca(2+) exchanger of mitochondria
|
| 133505 |
calcium ion import
|
|
increases_activity of
|
MAP2 proteolysis
|
in adult rat hippocampal slice; in direct response to NMDA receptor activation
|
|
12834896
|
Neurological
Alzheimer disease
|
|
14,210
|
| 134156 |
Angiotensin II
|
|
increases_activity of
|
calcium ion import
|
in vascular smooth muscle cells
|
|
22590974
|
Cardiovascular disease
|
|
15,715
|
| 149117 |
APOE4 (isoform E4)
|
|
increases_activity of
|
calcium ion import
|
in cytoplasm
|
|
|
Alzheimer disease
|
|
15,884
|
| 151455 |
voltage-gated calcium channel complex
|
|
increases_activity of
|
calcium ion import
|
when activated via insoluble aggregates of tau incorporated into the membrane
|
| 151456 |
calcium ion import
|
|
increases_quantity of
|
Reactive oxygen species
|
when insoluble aggregates of tau are incorporated into the membrane
|
| 151457 |
calcium ion import
|
|
affects_activity of
|
calcium-mediated signaling
|
|
| 151460 |
voltage-gated calcium channel complex
|
|
increases_activity of
|
calcium ion import
|
into neuron; concerning extracelluar Ca+2
|
| 151462 |
calcium channel complex
|
|
increases_activity of
|
calcium ion import
|
into cytosol; concerning extracelluar Ca+2
|
| 151565 |
calcium ion import
|
|
affects_activity of
|
calcium ion homeostasis
|
in neurons
|
|
|
Alzheimer disease
|
CIDeRplus