1,507
|
10648 |
DNA methylation
|
|
affects_expression of
|
SNCA
|
|
10650 |
Parkinson disease
|
|
decreases_activity of
|
DNA methylation
|
of SNCA intron 1
|
|
20445061
|
Parkinson disease
|
4,830
|
47707 |
Cocaine
|
|
increases_activity of
|
DNA methylation
|
repressing protein phosphatase-1Cbeta
|
|
23688924
|
Neurological
|
5,966
|
56123 |
Borderline personality disorder
|
|
affects_activity of
|
DNA methylation
|
at CpG sites; of EP400
|
|
25612291
|
Neurological
|
6,149
|
57503 |
DNA methylation
|
|
decreases_expression of
|
ACTA2
|
via decreased binding of MECP2 to alpha-SMA promoter
|
|
21435439
|
Lung disease
|
6,158
|
57608 |
DNA methylation
|
|
affects_activity of
|
FBLN2
|
in certain carcinomas
|
|
|
Cancer
Metabolic
|
6,316
|
59282 |
Acetaldehyde
|
|
decreases_activity of
|
DNA methylation
|
|
|
25427913
|
Alcohol dependence
Colorectal cancer
Pancreatic cancer
|
7,303
|
71623 |
aging
|
|
increases_activity of
|
DNA methylation
|
|
|
27029739
|
Diabetes mellitus, type II
Insulin resistance
|
7,426
|
73042 |
vascular endothelial cell response to laminar fluid shear stress
|
|
decreases_activity of
|
DNA methylation
|
in carotid arteries; at promoter sites
|
|
|
Cardiovascular disease
Atherosclerosis
|
7,517
|
74168 |
DNA methylation
|
|
affects_expression of
|
PRKCZ
|
in a North American population,but not in an independent Mediterranean cohort.
|
|
25075435
|
Metabolic
|
7,587
|
75497 |
Arachidonic acid
|
|
affects_activity of
|
DNA methylation
|
|
75519 |
Oleic acid
|
|
affects_activity of
|
DNA methylation
|
|
|
27088456
|
Diabetes mellitus, type II
Insulin resistance
Atherosclerosis
|
7,592
|
75864 |
decreased birth weight
|
|
affects_activity of
|
DNA methylation
|
|
|
20410232
|
Diabetes mellitus, type II
Insulin resistance
|
7,593
|
75553 |
Obesity
|
|
increases_activity of
|
DNA methylation
|
at different CpG sites of CLOCK, ARNTL and PER2
|
|
23003921
|
Diabetes mellitus, type II
Obesity
Insulin resistance
|
7,594
|
75557 |
long-chain omega-3 polyunsaturated fatty acid supplementation
|
|
affects_activity of
|
DNA methylation
|
|
75873 |
olive oil supplementation
|
|
affects_activity of
|
DNA methylation
|
|
75882 |
sex
|
|
affects_activity of
|
DNA methylation
|
|
|
25329159
|
Diabetes mellitus, type II
Insulin resistance
|
7,601
|
75946 |
dietary fat quantity and quality
|
|
affects_activity of
|
DNA methylation
|
|
|
25074463
|
Diabetes mellitus, type II
Obesity
Insulin resistance
Cardiovascular disease
|
7,729
|
77236 |
maternal hyperglycemia
|
|
decreases_activity of
|
DNA methylation
|
on fetal side of the placenta; in the ADIPOQ promoter
|
77241 |
Insulin resistance
|
|
decreases_activity of
|
DNA methylation
|
on maternal side of the placenta; in the ADIPOQ promoter
|
77244 |
DNA methylation
|
|
decreases_expression of
|
ADIPOQ
|
|
|
22396200
|
Diabetes mellitus, type II
Insulin resistance
Gestational diabetes mellitus
|
8,259
|
83399 |
Selenium
|
|
increases_activity of
|
DNA methylation
|
in liver
|
83403 |
S-Adenosylmethionine
|
|
increases_activity of
|
DNA methylation
|
|
|
28810182
|
Diabetes mellitus, type II
Metabolic
Insulin resistance
|
8,584
|
88487 |
Betaine
|
|
affects_activity of
|
DNA methylation
|
|
|
24456734
|
Fatty liver disease, nonalcoholic
|
8,969
|
94186 |
Adenosine
|
|
affects_activity of
|
DNA methylation
|
|
94187 |
transmethylation pathway
|
|
affects_activity of
|
DNA methylation
|
|
|
29522447
|
Severe combined immunodeficiency due to adenosine deaminase deficiency
|
9,796
|
103592 |
UHRF1
|
|
affects_activity of
|
DNA methylation
|
|
103593 |
UHRF2
|
|
affects_activity of
|
DNA methylation
|
|
|
31024001
|
Cancer
|
10,914
|
111279 |
S-Adenosylmethionine
|
|
increases_activity of
|
DNA methylation
|
|
|
24532461
|
Cancer
|
12,164
|
119196 |
SSPN rs718314
|
|
affects_activity of
|
DNA methylation
|
|
|
29932866
|
Diabetes mellitus, type II
Insulin resistance
|
13,810
|
129804 |
DNA methylation
|
|
affects_activity of
|
UNC13B
|
in diabetic nephropathy
|
129850 |
DNA methylation
|
|
affects_activity of
|
TGFB1
|
in diabetic nephropathy
|
129851 |
DNA methylation
|
|
affects_activity of
|
renal fibrosis
|
in diabetic nephropathy
|
129856 |
DNA methylation
|
|
increases_activity of
|
Ras protein signal transduction
|
in fibroblasts
|
|
25003613
|
Nephropathy, diabetic
|
14,593
|
137348 |
DNMT3L
|
|
increases_activity of
|
DNA methylation
|
in embryonic stem cells
|
|
30321403
|
Developmental disorder
|