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Field	Query

	Field	Term

General Information:

Id:	9,171
Diseases:	Metabolic
Organism:	Homo sapiens
Gender:	male
Organism Model:	6 healthy subjects
Publication type:	article
Reference:	Kaya M et al.(2006) Plasma concentrations and urinary excretion of purine bases (uric acid, hypoxanthine, and xanthine) and oxypurinol after rigorous exercise Metab. Clin. Exp. 55: 103-107 [PMID: 16324927]

Interaction Information:

Comment	Exercise (VO2max 70%) increased the plasma concentrations of hypoxanthine, xanthine, urate.
Formal Description Interaction-ID: 97265	environment high-intensity exercise increases_quantity of drug/chemical compound Hypoxanthine in plasma
Drugbank entries	Show/Hide entries for
Drugbank DB04076	Hypoxanthine not specified PNP
Drugbank DB04076	Hypoxanthine not specified PNP

Comment	Exercise (VO2max 70%) increased the plasma concentrations of hypoxanthine, xanthine and urate.
Formal Description Interaction-ID: 97293	environment high-intensity exercise increases_quantity of drug/chemical compound Xanthine in plasma
Drugbank entries	Show/Hide entries for
Drugbank DB02134	Xanthine not specified xapA
Drugbank DB02134	Xanthine not specified gpt
Drugbank DB02134	Xanthine not specified xapA
Drugbank DB02134	Xanthine not specified gpt

Comment	Exercise (VO2max 70%) increased the plasma concentrations of hypoxanthine, xanthine and urate.
Formal Description Interaction-ID: 97300	environment high-intensity exercise increases_quantity of drug/chemical compound Urate in plasma

Comment	Exercise increased the urinary excretion of hypoxanthine, xanthine and decreased the urinary excretion of uric acid.
Formal Description Interaction-ID: 97301	environment high-intensity exercise increases_transport of drug/chemical compound Hypoxanthine by urinary excretion
Drugbank entries	Show/Hide entries for
Drugbank DB04076	Hypoxanthine not specified PNP
Drugbank DB04076	Hypoxanthine not specified PNP

Comment	Exercise increased the urinary excretion of hypoxanthine, xanthine and decreased the urinary excretion of uric acid.
Formal Description Interaction-ID: 97302	environment high-intensity exercise increases_transport of drug/chemical compound Xanthine by urinary excretion
Drugbank entries	Show/Hide entries for
Drugbank DB02134	Xanthine not specified xapA
Drugbank DB02134	Xanthine not specified gpt
Drugbank DB02134	Xanthine not specified xapA
Drugbank DB02134	Xanthine not specified gpt

Comment	Exercise increased the urinary excretion of hypoxanthine, xanthine and decreased the urinary excretion of uric acid. Reduced urinary excretion of uric acid may lead to higher levels of uric acid in plasma.
Formal Description Interaction-ID: 97303	environment high-intensity exercise decreases transport of drug/chemical compound Urate by urinary excretion

Comment	Exercise increases the concentration of lactic acid in blood.
Formal Description Interaction-ID: 97304	environment high-intensity exercise increases_quantity of drug/chemical compound Lactate in blood

Comment	Exercise increases the concentration of noradrenaline in plasma.
Formal Description Interaction-ID: 97305	environment high-intensity exercise increases_quantity of drug/chemical compound Noradrenaline in plasma

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