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Field	Query

	Field	Term

General Information:

Id:	908 (click here to show other Interactions for entry)
Diseases:	Alzheimer disease - [OMIM]
Organism:	Mammalia
Publication type:	review
Reference:	Sun AY et al.(2008) Botanical phenolics and brain health Neuromolecular Med. 10: 259-274 [PMID: 19191039]

Interaction Information:

Comment	Increase in oxidative stress is associated with early development of Alzheimer's disease.
Formal Description Interaction-ID: 5414	disease Alzheimer disease increases_activity of process response to oxidative stress

Comment	One part of the oxidative mechanism affects the quantity of amyloid beta peptides (39-43 aa).
Formal Description Interaction-ID: 5416	process response to oxidative stress affects_quantity of gene/protein Amyloid beta peptide (39-43)

Comment	Curcumin offers antioxidant, anti-inflammatory and cholesterol lowering properties, all are important on ameliorating the deleterious consequences of AD.
Formal Description Interaction-ID: 5557	drug/chemical compound Curcumin increases_activity of process response to oxidative stress

Comment	One part of the oxidative mechanism affects the quantity of amyloid beta peptides (39-43 aa).
Formal Description Interaction-ID: 10906	process response to oxidative stress affects_quantity of gene/protein Amyloid beta peptide (42)

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