General Information:

Id: 861 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
brain
article
Reference: Pei JJ et al.(2003) Role of protein kinase B in Alzheimers neurofibrillary pathology. Acta Neuropathol. 105: 381-392 [PMID: 12624792]

Interaction Information:

Comment Both active PKB and GSK-3alpha/beta preceded the abnormal hyperphosphorylation of tau in pattern 1 neurons.
Formal Description
Interaction-ID: 5119

gene/protein

AKT1

increases_quantity of

protein modification

MAPT-hyperphos

Drugbank entries Show/Hide entries for AKT1