CIDeRplusGeneral Information:
| Id: | 861 (click here to show other Interactions for entry) |
| Diseases: |
Alzheimer disease
- [OMIM]
|
| Homo sapiens | |
| brain | |
| article | |
| Reference: | Pei JJ et al.(2003) Role of protein kinase B in Alzheimers neurofibrillary pathology. Acta Neuropathol. 105: 381-392 [PMID: 12624792] |
Interaction Information:
| Comment | Protein kinase B (PKB) is an important intermediate in the phosphatidylinositol-3 kinase signaling cascade that acts to phosphorylate glycogen synthase kinase-3 (GSK-3) at its serine 9 residue, thereby inactivating it. |
|
Formal Description Interaction-ID: 5117 |
gene/protein affects_phosphorylation of gene/protein GSK3 |
| Drugbank entries | Show/Hide entries for AKT1 |