General Information:

Id: 852 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Homo sapiens
BTO:0000772 lymphoblast from human PD patients harboring DJ-1 mutations
article
Reference: Aleyasin H et al.(2010) DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway. Proc. Natl. Acad. Sci. U.S.A. 107: 3186-3191 [PMID: 20133695]

Interaction Information:

Comment Phosphorylation of AKT1 in response to H2O2 was significantly attenuated in DJ-1-L166P mutated cells compared to the controls.
Formal Description
Interaction-ID: 5072

gene/protein mutant

PARK7-p.L166P

NOT increases_phosphorylation of

gene/protein

AKT1

in response to H2O2
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