BTO:0000772 lymphoblast from human PD patients harboring DJ-1 mutations
article
Reference:
Aleyasin H et al.(2010) DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway. Proc. Natl. Acad. Sci. U.S.A. 107: 3186-3191
[PMID: 20133695]
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Comment
Phosphorylation of AKT1 in response to H2O2 was significantly attenuated in DJ-1-L166P mutated cells compared to the controls.