General Information:

Id: 8,418 (click here to show other Interactions for entry)
Diseases: Metabolic
Mus musculus
article/cited
Reference: Urayama A et al.(2008) Mannose 6-phosphate receptor-mediated transport of sulfamidase across the blood-brain barrier in the newborn mouse Mol. Ther. 16: 1261-1266 [PMID: 18443601]

Interaction Information:

Comment Sulfamidase (N-sulfoglucosamine sulfohydrolase; EC 3.10.1.1) cleaves N-linked sulfates from nonreducing terminals of heparan sulfates. The native enzyme forms a 115 kd dimer, composed of two 62 kd monomers, 1,2 each with five N-glycosylation sites.
Formal Description
Interaction-ID: 85710

complex/PPI

Sulfamidase

decreases_quantity of

drug/chemical compound

Heparan sulfate

via cleaving N-linked sulfates from nonreducing terminals of heparan sulfates