General Information:

Id: 8,316 (click here to show other Interactions for entry)
Diseases: Propionic acidemia - [OMIM]
Mammalia
review
Reference: Wongkittichote P et al.(2017) Propionyl-CoA carboxylase - A review Mol. Genet. Metab. 122: 145-152 [PMID: 29033250]

Interaction Information:

Comment Alpha-ketoglutarate (2-Oxoglutarate), which is converted to succinyl-CoA, plays an important role in anaplerosis in the brain, given that the alpha-ketoglutarate pool contributes to production of GABA and glutamine.
Formal Description
Interaction-ID: 84412

drug/chemical compound

2-Oxoglutarate

increases_quantity of

drug/chemical compound

GABA