General Information:

Id: 8,285 (click here to show other Interactions for entry)
Diseases: Cardiovascular disease
Diabetes mellitus, type II - [OMIM]
Fatty liver disease, nonalcoholic
Insulin resistance
Mammalia
review
Reference: Kempson SA et al.(2014) The betaine/GABA transporter and betaine: roles in brain, kidney, and liver Front Physiol 5: 159 [PMID: 24795654]

Interaction Information:

Comment The physiological roles of the betaine/GABA transporter (BGT1; slc6a12) are still being debated. BGT1 is a member of the solute carrier family 6 (the neurotransmitter, sodium symporter transporter family) and mediates cellular uptake of betaine and GABA in a sodium- and chloride-dependent process.
Formal Description
Interaction-ID: 84155

gene/protein

SLC6A12

increases_transport of

drug/chemical compound

GABA

into the cell