General Information:

Id: 824 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mammalia
review
Reference: Sugden MC et al.(2010) PPAR control: its SIRTainly as easy as PGC J Endocrinol 204: 93-104 [PMID: 19770177]

Interaction Information:

Comment AKT/PKB-mediated phosphorylation facilitates degradation of hepatic PGC-1alpha.
Formal Description
Interaction-ID: 4802

gene/protein

AKT1

decreases_quantity of

gene/protein

PPARGC1A

in liver; via increased degradation of PPARGC1A
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