CIDeRplusGeneral Information:
| Id: | 8,083 |
| Diseases: |
Alzheimer disease
- [OMIM]
|
| Homo sapiens | |
| BTO:0000237 cerebrospinal fluid | |
| review | |
| Reference: | Enche Ady CNA et al.(2017) Metabolomic-guided discovery of Alzheimers disease biomarkers from body fluid J. Neurosci. Res. 95: 2005-2024 [PMID: 28301062] |
Interaction Information:
| Comment | The concentration L-phenylalanine was decreased in brain homogenates of Alzheimer disease (AD) patients with gradual pre-mortem memory loss compared to heathy controls. |
|
Formal Description Interaction-ID: 80550 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration L-lactic acid was increased in brain homogenates of AD patients with gradual pre-mortem memory loss compared to heathy controls. |
|
Formal Description Interaction-ID: 80551 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration guanine was increased in brain of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80552 |
disease increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The concentration of deoxyguanosine was decreased in brain of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80554 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of inosine diphosphate was decreased in brain of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80555 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of xanthosine was decreased in brain of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80556 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of 2-deoxyguanosine 5-monophosphate was decreased in brain of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80560 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of glycine was decreased in brain of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80565 |
disease decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The concentration of glycine was increased in brain of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80566 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of taurine was increased in brain of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80568 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of sphingosine-1-phosphate was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80575 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of caproic acid was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80576 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of tryptophan was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80661 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of pipecolic acid was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80662 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of nonanoylglycine was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80663 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of taurine was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80666 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of uridine was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80668 |
disease increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The concentration of uracil was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80669 |
disease decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The concentration of methylthioadenosine was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80671 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of dopamine-quinone was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80673 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of tyrosil-serine was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80674 |
disease increases_quantity of gene/protein TYR-SER |
| Comment | The concentration of hydroxyphosphinyl-pyruvate was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80716 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of vanylglycol was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80720 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of xanthine was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80724 |
disease decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The concentration of creatinine was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80725 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of methylsalsolinol was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80729 |
disease decreases_quantity of drug/chemical compound Methylsalsolinol |
| Comment | The concentration of methionine was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80737 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of gluthathione was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80739 |
disease increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The concentration of 5-hydroxyindoleacetic acid was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80741 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of vanillylmandelic acid was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80743 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of xanthosine was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80816 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of serine was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80819 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of valine was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80822 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of choline was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80823 |
disease increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The concentration of tripeptide (Gly-Thr-Met) was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80824 |
disease increases_quantity of drug/chemical compound Gly-Thr-Met |
| Comment | The concentration of tripeptide (Val-Ser-Cys) was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80826 |
disease increases_quantity of gene/protein Val-Ser-Cys |
| Comment | The concentration of tripeptide (Met-Ser-Ala) was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80827 |
disease increases_quantity of gene/protein Met-Ser-Ala |
| Comment | The concentration of 5-hydroxytryptophan was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80828 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of methoxy-hydroxyphenyl glycol was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80831 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of norepinephrine was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80832 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of 3-methoxytyramine was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80834 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of alpha tocopherol was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80836 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of ascorbate was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80837 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of succinic anhydride was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80838 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of dehydroascorbic acid was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80839 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of was arecoline increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80840 |
disease increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The concentration of N-methyl-L-lysine was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80845 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of pyruvic acid was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80851 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of acetoacetic acid was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80858 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of citraconic acid was increased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80860 |
disease increases_quantity of drug/chemical compound |
| Comment | The concentration of 7-hydroxy tetranoriloprost (Ventavis) was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80862 |
disease decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for |
| Comment | The concentration of 2-octenedioic acid was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 80871 |
disease decreases_quantity of drug/chemical compound 2-octenedioic acid |
| Comment | The concentration of prostaglandine2-alpha dimethyl amine was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 81242 |
disease decreases_quantity of drug/chemical compound prostaglandine2-alpha dimethyl amine |
| Comment | The concentration of pyrogallin was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 81244 |
disease decreases_quantity of drug/chemical compound pyrogallin |
| Comment | The concentration of methyl 7-deshydroxypyrogallin-4-carboxylate was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 81245 |
disease decreases_quantity of drug/chemical compound methyl 7-deshydroxypyrogallin-4-carboxylate |
| Comment | The concentration of 2-hydroxy-3-4-methoxyethylphenoxy-propanoic acid was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 81246 |
disease decreases_quantity of drug/chemical compound methyl 7-deshydroxypyrogallin-4-carboxylate |
| Comment | The concentration of anthracene was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 81247 |
disease decreases_quantity of drug/chemical compound Antracene |
| Comment | The concentration of 1-hydro-2-naphtoic acid was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 81248 |
disease decreases_quantity of drug/chemical compound 1-hydro-2-naphtoic acid |
| Comment | The concentration of methosxalen was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 81249 |
disease decreases_quantity of drug/chemical compound |
| Comment | The concentration of vitamin D3 derivatives was decreased in CSF of AD patients compared to healthy controls. |
|
Formal Description Interaction-ID: 83199 |
disease decreases_quantity of drug/chemical compound Vitamin D3 derivatives |