CIDeRplusGeneral Information:
| Id: | 7,598 (click here to show other Interactions for entry) |
| Diseases: |
Alzheimer disease
- [OMIM]
Gastrointestinal Mental Metabolic |
| Mammalia | |
| review | |
| Reference: | Pistollato F et al.(2016) Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease Nutr. Rev. 74: 624-634 [PMID: 27634977] |
Interaction Information:
| Comment | Some bacterial species, such as Lactobacillus and Bifidobacterium (both gram-positive facultative anaerobic or microaerophilic bacteria), can metabolize glutamate to produce gamma aminobutyric acid (GABA), the major inhibitory neurotransmitter, and alterations of gut microbiota might compromise the endogenous production of GABA and short-chain fatty acids (ie, acetate, butyrate, and propionate). |
|
Formal Description Interaction-ID: 76458 |
|