General Information:

Id: 7,522 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Metabolic
Mammalia
review
Reference: Raber J(2008) AR, apoE, and cognitive function Horm Behav 53: 706-715 [PMID: 18395206]

Interaction Information:

Comment Compared to age-matched wild-type and Apoe-/- mice, expression of apoE4, but not apoE3, reduces cytosolic AR binding to androgens in the neocortex of female and male mice
Formal Description
Interaction-ID: 74185

gene/protein mutant

APOE (isoform E4)

decreases_activity of

gene/protein

AR

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