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Field	Query

	Field	Term

General Information:

Id:	743
Diseases:	Amyotrophic lateral sclerosis
Organism:	Homo sapiens
Tissue/Cell line:	BTO:0000131 blood plasma
Publication type:	poster
Reference:	[PMID: 0]

Interaction Information:

Comment	To discover metabolic biomarkers that provide diagnostic and therapeutic benefits to ALS metabolomic analysis was carried out on over 350 plasma samples collected from ALS patients and healthy control subjects. Using LC-MS and GC-MS platforms metabolic signatures characteristic for ALS were discovered.
Formal Description Interaction-ID: 4190	disease Amyotrophic lateral sclerosis increases_quantity of drug/chemical compound Glutamate in blood serum

Comment	To discover metabolic biomarkers that provide diagnostic and therapeutic benefits to ALS metabolomic analysis was carried out on over 350 plasma samples collected from ALS patients and healthy control subjects. Using LC-MS and GC-MS platforms metabolic signatures characteristic for ALS were discovered.
Formal Description Interaction-ID: 4191	disease Amyotrophic lateral sclerosis increases_quantity of drug/chemical compound Arachidonic acid in blood serum
Drugbank entries	Show/Hide entries for
Drugbank DB04557	Arachidonic Acid not specified PTGS1
Drugbank DB04557	Arachidonic Acid not specified ""
Drugbank DB04557	Arachidonic Acid not specified ""
Drugbank DB04557	Arachidonic Acid not specified PTGS1

Comment	To discover metabolic biomarkers that provide diagnostic and therapeutic benefits to ALS metabolomic analysis was carried out on over 350 plasma samples collected from ALS patients and healthy control subjects. Using LC-MS and GC-MS platforms metabolic signatures characteristic for ALS were discovered.
Formal Description Interaction-ID: 4192	disease Amyotrophic lateral sclerosis increases_quantity of drug/chemical compound Xanthine in blood serum
Drugbank entries	Show/Hide entries for
Drugbank DB02134	Xanthine not specified xapA
Drugbank DB02134	Xanthine not specified gpt
Drugbank DB02134	Xanthine not specified xapA
Drugbank DB02134	Xanthine not specified gpt

Comment	To discover metabolic biomarkers that provide diagnostic and therapeutic benefits to ALS metabolomic analysis was carried out on over 350 plasma samples collected from ALS patients and healthy control subjects. Using LC-MS and GC-MS platforms metabolic signatures characteristic for ALS were discovered.
Formal Description Interaction-ID: 4193	disease Amyotrophic lateral sclerosis decreases_quantity of drug/chemical compound Carnosine in blood serum

Comment	To discover metabolic biomarkers that provide diagnostic and therapeutic benefits to ALS metabolomic analysis was carried out on over 350 plasma samples collected from ALS patients and healthy control subjects. Using LC-MS and GC-MS platforms metabolic signatures characteristic for ALS were discovered.
Formal Description Interaction-ID: 4194	disease Amyotrophic lateral sclerosis decreases_quantity of drug/chemical compound N6,N6,N6-Trimethyl-L-lysine in blood serum

Comment	To discover metabolic biomarkers that provide diagnostic and therapeutic benefits to ALS metabolomic analysis was carried out on over 350 plasma samples collected from ALS patients and healthy control subjects. Using LC-MS and GC-MS platforms metabolic signatures characteristic for ALS were discovered.
Formal Description Interaction-ID: 4196	disease Amyotrophic lateral sclerosis decreases_quantity of drug/chemical compound 3-(4-Hydroxyphenyl)lactate in blood serum

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