CIDeRplusGeneral Information:
| Id: | 7,322 (click here to show other Interactions for entry) |
| Diseases: |
Alzheimer disease
- [OMIM]
|
| Mammalia | |
| review | |
| Reference: | Mielke MM et al.(2014) Clinical epidemiology of Alzheimers disease: assessing sex and gender differences Clin Epidemiol 6: 37-48 [PMID: 24470773] |
Interaction Information:
| Comment | The effects of the E4 genotype are more pronounced in women than in men. Three studies reported that women with one E4 allele had about a four-fold risk of AD, whereas men with one E4 allele showed little increased risk. |
|
Formal Description Interaction-ID: 71968 |
phenotype sex, female increases_activity of gene/protein mutant |