General Information:

Id: 7,255 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Metabolic
Mammalia
review
Reference: Phillips MC(2014) Apolipoprotein E isoforms and lipoprotein metabolism IUBMB Life 66: 616-623 [PMID: 25328986]

Interaction Information:

Comment ApoE4 binds much better than apoE3 to VLDL but somewhat less well than apoE3 to HDL.
Formal Description
Interaction-ID: 71436

gene/protein mutant

APOE (isoform E4)

decreases_activity of

process

high-density lipoprotein particle binding

compared to apoE3; ApoE4 binds much better than apoE3 to VLDL but somewhat less well than apoE3 to HDL