General Information:

Id: 717
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
BTO:0000007 HEK-293 cell
article
Reference: Su Y et al.(2004) Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing Biochemistry 43: 6899-6908 [PMID: 15170327]

Interaction Information:

Comment Lithium regulates amyloid-beta precursor protein (APP) processing.
Formal Description
Interaction-ID: 4011

drug/chemical compound

Lithium

affects_processing of

gene/protein

APP

Drugbank entries Show/Hide entries for Lithium or APP
Comment Valproic acid (VPA) regulates amyloid-beta precursor protein (APP) processing.
Formal Description
Interaction-ID: 4012

drug/chemical compound

Valproic acid

affects_processing of

gene/protein

APP

Drugbank entries Show/Hide entries for Valproic acid or APP
Comment Lithium lowers the amyloid-beta peptide production.
Formal Description
Interaction-ID: 4016

drug/chemical compound

Lithium

decreases_quantity of

gene/protein

Amyloid beta peptide (40)

Drugbank entries Show/Hide entries for Lithium
Comment Valproic acid (VPA) lowers the amyloid-beta peptide production.
Formal Description
Interaction-ID: 4017

drug/chemical compound

Valproic acid

decreases_quantity of

gene/protein

Amyloid beta peptide (40)

Drugbank entries Show/Hide entries for Valproic acid
Comment Lithium lowers the amyloid-beta peptide production.
Formal Description
Interaction-ID: 10902

drug/chemical compound

Lithium

decreases_quantity of

gene/protein

Amyloid beta peptide (42)

Drugbank entries Show/Hide entries for Lithium
Comment Valproic acid (VPA) lowers the amyloid-beta peptide production.
Formal Description
Interaction-ID: 10903

drug/chemical compound

Valproic acid

decreases_quantity of

gene/protein

Amyloid beta peptide (42)

Drugbank entries Show/Hide entries for Valproic acid