General Information:

Id: 713 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1 wt or SOD1G93A transgenic mouse, transfected with human wt SOD1 or human SOD1G93A
BTO:0001279 spinal cord
article
Reference: Lee J et al.(2009) Activation of Ets-2 by oxidative stress induces Bcl-xL expression and accounts for glial survival in amyotrophic lateral sclerosis FASEB J. 23: 1739-1749 [PMID: 19179380]

Interaction Information:

Comment Bcl-xL induction rescues primary astrocytes from oxidative stress-induced cell damage and death.
Formal Description
Interaction-ID: 4004

gene/protein

BCL2L1

decreases_activity of

process

response to oxidative stress

in primary astrocytes
Drugbank entries Show/Hide entries for BCL2L1