CIDeRplusGeneral Information:
| Id: | 654 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Fatty liver disease, nonalcoholic Insulin resistance Obesity - [OMIM] |
| Mammalia | |
| review | |
| Reference: | Chen HC and Farese RV Jr(2005) Inhibition of triglyceride synthesis as a treatment strategy for obesity: lessons from DGAT1-deficient mice. Arterioscler. Thromb. Vasc. Biol. 25: 482-486 [PMID: 15569818] |
Interaction Information:
| Comment | Insulin-stimulated glucose transport is increased in skeletal muscle and white adipose tissue of DGAT1-/- mice, and insulin-stimulated activities of phosphatidylinositol-3 kinase, protein kinase B, and protein kinase C-delta, three key molecules in the insulin signaling pathway, are also increased in the skeletal muscle of DGAT1-/- mice. |
|
Formal Description Interaction-ID: 3511 |
|
| Drugbank entries | Show/Hide entries for AKT1 |