General Information:

Id: 6,422
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
article
Reference: Nedeltcheva AV et al.(2009) Exposure to recurrent sleep restriction in the setting of high caloric intake and physical inactivity results in increased insulin resistance and reduced glucose tolerance J. Clin. Endocrinol. Metab. 94: 3242-3250 [PMID: 19567526]

Interaction Information:

Comment The study included two 14-d periods of controlled exposure to sedentary living with ad libitum food intake and 5.5- or 8.5-h bedtimes. Exposure to recurrent sleep restriction in the setting of high caloric intake and physical inactivity results in increased insulin resistance and reduced glucose tolerance.
Formal Description
Interaction-ID: 60527

environment

recurrent sleep restriction

increases_activity of

disease

Insulin resistance

in a setting of high caloric intake and physical inactivity
Comment The study included two 14-d periods of controlled exposure to sedentary living with ad libitum food intake and 5.5- or 8.5-h bedtimes. Exposure to recurrent sleep restriction in the setting of high caloric intake and physical inactivity results in increased insulin resistance and reduced glucose tolerance.
Formal Description
Interaction-ID: 60528

environment

recurrent sleep restriction

increases_activity of

in a setting of high caloric intake and physical inactivity
Comment Although 24-h cortisol and GH concentrations did not change, there was a modest increase in 24-h epinephrine and nighttime norepinephrine levels during the 5.5-h bedtime condition.
Formal Description
Interaction-ID: 60529

environment

recurrent sleep restriction

increases_quantity of

drug/chemical compound

Adrenaline

in a setting of high caloric intake and physical inactivity
Comment Although 24-h cortisol and GH concentrations did not change, there was a modest increase in 24-h epinephrine and nighttime norepinephrine levels during the 5.5-h bedtime condition.
Formal Description
Interaction-ID: 60530

environment

recurrent sleep restriction

increases_quantity of

drug/chemical compound

Noradrenaline

in a setting of high caloric intake and physical inactivity