General Information:
Id: | 6,422 |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
Homo sapiens | |
article | |
Reference: | Nedeltcheva AV et al.(2009) Exposure to recurrent sleep restriction in the setting of high caloric intake and physical inactivity results in increased insulin resistance and reduced glucose tolerance J. Clin. Endocrinol. Metab. 94: 3242-3250 [PMID: 19567526] |
Interaction Information:
Comment | The study included two 14-d periods of controlled exposure to sedentary living with ad libitum food intake and 5.5- or 8.5-h bedtimes. Exposure to recurrent sleep restriction in the setting of high caloric intake and physical inactivity results in increased insulin resistance and reduced glucose tolerance. |
Formal Description Interaction-ID: 60527 |
environment recurrent sleep restriction increases_activity of disease Insulin resistance |
Comment | The study included two 14-d periods of controlled exposure to sedentary living with ad libitum food intake and 5.5- or 8.5-h bedtimes. Exposure to recurrent sleep restriction in the setting of high caloric intake and physical inactivity results in increased insulin resistance and reduced glucose tolerance. |
Formal Description Interaction-ID: 60528 |
environment recurrent sleep restriction increases_activity of phenotype |
Comment | Although 24-h cortisol and GH concentrations did not change, there was a modest increase in 24-h epinephrine and nighttime norepinephrine levels during the 5.5-h bedtime condition. |
Formal Description Interaction-ID: 60529 |
environment recurrent sleep restriction increases_quantity of drug/chemical compound |
Comment | Although 24-h cortisol and GH concentrations did not change, there was a modest increase in 24-h epinephrine and nighttime norepinephrine levels during the 5.5-h bedtime condition. |
Formal Description Interaction-ID: 60530 |
environment recurrent sleep restriction increases_quantity of drug/chemical compound |