General Information:
Id: | 6,356 (click here to show other Interactions for entry) |
Diseases: |
Prostate cancer
- [OMIM]
|
Homo sapiens | |
DU-145 prostate cancer cell | |
article | |
Reference: | Makarevic J et al.(2014) Cross-communication between histone H3 and H4 acetylation and Akt-mTOR signalling in prostate cancer cells J. Cell. Mol. Med. 18: 1460-1466 [PMID: 24779401] |
Interaction Information:
Comment | DU-145 prostate cancer cells were treated with insulin-like growth factor (IGF) to activate the Akt-mTOR cascade or with the HDAC-inhibitor valproic acid (VPA) to induce histone H3 and H4 acetylation (aH3, aH4). |
Formal Description Interaction-ID: 59565 |
drug/chemical compound increases_activity of process |
Drugbank entries | Show/Hide entries for Valproic acid |