General Information:

Id: 6,356 (click here to show other Interactions for entry)
Diseases: Prostate cancer - [OMIM]
Homo sapiens
DU-145 prostate cancer cell
article
Reference: Makarevic J et al.(2014) Cross-communication between histone H3 and H4 acetylation and Akt-mTOR signalling in prostate cancer cells J. Cell. Mol. Med. 18: 1460-1466 [PMID: 24779401]

Interaction Information:

Comment VPA (HDAC-inhibitor valproic acid) treatment up-regulated histone acetylation, but also activated mTOR-Akt signalling.
Formal Description
Interaction-ID: 59558

drug/chemical compound

Valproic acid

increases_activity of

process

AKT/TOR signaling

in DU-145 prostata cancer cells
Drugbank entries Show/Hide entries for Valproic acid