General Information:

Id: 6,333
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
article/cited
Reference: Lee HJ et al.(2011) Serotonin induces melanogenesis via serotonin receptor 2A Br. J. Dermatol. 165: 1344-1348 [PMID: 21711335]

Interaction Information:

Comment Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from L-tryptophan. The actions of 5-HT are mediated via an interaction with receptors, which include seven families (5-HTR1‚Äď7) with at least 21 subtypes. Skin cells express mRNA encoding 5-HT receptors, 5-HTR1A, -1B, -2A, -2B, -2C and -7. (cited information)
Formal Description
Interaction-ID: 59401

gene/protein

HTR1A

is_expressed_in

tissue/cell line

skin

Drugbank entries Show/Hide entries for HTR1A
Comment Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from L-tryptophan. The actions of 5-HT are mediated via an interaction with receptors, which include seven families (5-HTR1‚Äď7) with at least 21 subtypes. Skin cells express mRNA encoding 5-HT receptors, 5-HTR1A, -1B, -2A, -2B, -2C and -7. (cited information)
Formal Description
Interaction-ID: 59402

gene/protein

HTR1B

is_expressed_in

tissue/cell line

skin

Drugbank entries Show/Hide entries for HTR1B
Comment Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from L-tryptophan. The actions of 5-HT are mediated via an interaction with receptors, which include seven families (5-HTR1‚Äď7) with at least 21 subtypes. Skin cells express mRNA encoding 5-HT receptors, 5-HTR1A, -1B, -2A, -2B, -2C and -7. (cited information)
Formal Description
Interaction-ID: 59403

gene/protein

HTR2A

is_expressed_in

tissue/cell line

skin

Drugbank entries Show/Hide entries for HTR2A
Comment Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from L-tryptophan. The actions of 5-HT are mediated via an interaction with receptors, which include seven families (5-HTR1‚Äď7) with at least 21 subtypes. Skin cells express mRNA encoding 5-HT receptors, 5-HTR1A, -1B, -2A, -2B, -2C and -7. (cited information)
Formal Description
Interaction-ID: 59404

gene/protein

HTR2B

is_expressed_in

tissue/cell line

skin

Drugbank entries Show/Hide entries for HTR2B
Comment Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from L-tryptophan. The actions of 5-HT are mediated via an interaction with receptors, which include seven families (5-HTR1‚Äď7) with at least 21 subtypes. Skin cells express mRNA encoding 5-HT receptors, 5-HTR1A, -1B, -2A, -2B, -2C and -7. (cited information)
Formal Description
Interaction-ID: 59405

gene/protein

HTR2C

is_expressed_in

tissue/cell line

skin

Drugbank entries Show/Hide entries for HTR2C
Comment Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from L-tryptophan. The actions of 5-HT are mediated via an interaction with receptors, which include seven families (5-HTR1‚Äď7) with at least 21 subtypes. Skin cells express mRNA encoding 5-HT receptors, 5-HTR1A, -1B, -2A, -2B, -2C and -7. (cited information)
Formal Description
Interaction-ID: 59406

gene/protein

HTR7

is_expressed_in

tissue/cell line

skin

Drugbank entries Show/Hide entries for HTR7
Comment Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from L-tryptophan. The actions of 5-HT are mediated via an interaction with receptors, which include seven families (5-HTR1‚Äď7) with at least 21 subtypes. Skin cells express mRNA encoding 5-HT receptors, 5-HTR1A, -1B, -2A, -2B, -2C and -7. (cited information)
Formal Description
Interaction-ID: 59407

gene/protein

HTR2A

interacts (colocalizes) with

drug/chemical compound

Serotonin

Drugbank entries Show/Hide entries for HTR2A