CIDeRplusGeneral Information:
| Id: | 611 |
| Diseases: |
Status epilepticus
|
| Rattus norvegicus | |
| Wistar | |
| BTO:0000601 hippocampus | |
| article | |
| Reference: | Costa MS et al.(2004) Pilocarpine-induced status epilepticus increases glutamate release in rat hippocampal synaptosomes. Neurosci. Lett. 356: 41-44 [PMID: 14746897] |
Interaction Information:
| Comment | Pilocarpine added to the medium did not modify the glutamate release profile. |
|
Formal Description Interaction-ID: 3226 |
drug/chemical compound NOT affects_activity of |
| Drugbank entries | Show/Hide entries for Pilocarpine |
| Comment | Animals presenting status epilepticus did not modify the glutamate uptake by synaptosomes. |
|
Formal Description Interaction-ID: 3230 |
disease Status epilepticus NOT affects_activity of |
| Comment | An increase in the glutamate efflux in the absence (1.43-fold) and in the presence of KCl (1.25-fold) was found in hippocampal synaptosomes due to status epilepticus in pilocarpine model of epilepsy. |
|
Formal Description Interaction-ID: 3235 |
disease Status epilepticus affects_activity of |