CIDeRplusGeneral Information:
| Id: | 596 |
| Diseases: |
Status epilepticus
|
| Rattus norvegicus | |
| Wistar | |
| BTO:0000601 hippocampus | |
| article | |
| Reference: | Cavalheiro EA et al.(1994) Spontaneous recurrent seizures in rats: amino acid and monoamine determination in the hippocampus. Epilepsia 35: 1-11 [PMID: 8112229] |
Interaction Information:
| Comment | Norepinephrine (NE) level was decreased during all periods afte pilocarpine administration whereas dopamine (DA) content was increased. |
|
Formal Description Interaction-ID: 3145 |
drug/chemical compound decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for Pilocarpine |
| Comment | Norepinephrine (NE) level was decreased during all periods afte pilocarpine administration whereas dopamine (DA) content was increased. |
|
Formal Description Interaction-ID: 3151 |
drug/chemical compound increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for Pilocarpine or Dopamine |
| Comment | Serotonin (5-hydroxytryptamine, 5-HT) was increased only in the acute period after pilocarpine administration. |
|
Formal Description Interaction-ID: 3152 |
drug/chemical compound increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for Pilocarpine |
| Comment | Amino acid content showed a decrease in aspartate (ASP) and glutamate (GLU) concentrations associated with increased gamma-aminobutyric acid (GABA) level during the acute period. |
|
Formal Description Interaction-ID: 3154 |
drug/chemical compound decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for Pilocarpine |
| Comment | Amino acid content showed a decrease in aspartate (ASP) and glutamate (GLU) concentrations associated with increased gamma-aminobutyric acid (GABA) level during the acute period. |
|
Formal Description Interaction-ID: 3155 |
drug/chemical compound decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for Pilocarpine |
| Comment | Amino acid content showed a decrease in aspartate (ASP) and glutamate (GLU) concentrations associated with increased gamma-aminobutyric acid (GABA) level during the acute period. |
|
Formal Description Interaction-ID: 3156 |
drug/chemical compound increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for Pilocarpine |
| Comment | The silent phase was characterized by a decrease in glycine (GLY) and GABA levels and an increase in GLU concentration. |
|
Formal Description Interaction-ID: 3163 |
drug/chemical compound decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for Pilocarpine or Glycine |
| Comment | The silent phase was characterized by a decrease in glycine (GLY) and GABA levels and an increase in GLU concentration. |
|
Formal Description Interaction-ID: 3164 |
drug/chemical compound decreases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for Pilocarpine |
| Comment | The silent phase was characterized by a decrease in glycine (GLY) and GABA levels and an increase in GLU concentration. |
|
Formal Description Interaction-ID: 3165 |
drug/chemical compound increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for Pilocarpine |
| Comment | The period of spontaneous recurrent seizures (SRS) showed an increase in all amino acid (Glu, Asp. GABA, Gln) concentrations. |
|
Formal Description Interaction-ID: 3194 |
drug/chemical compound increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for Pilocarpine |
| Comment | The period of spontaneous recurrent seizures (SRS) showed an increase in all amino acid (Glu, Asp. GABA, Gln) concentrations. |
|
Formal Description Interaction-ID: 3198 |
drug/chemical compound increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for Pilocarpine or Glycine |
| Comment | The period of spontaneous recurrent seizures (SRS) showed an increase in all amino acid (Glu, Asp. GABA, Gln) concentrations. |
|
Formal Description Interaction-ID: 3202 |
drug/chemical compound increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for Pilocarpine |
| Comment | The period of spontaneous recurrent seizures (SRS) showed an increase in all amino acid (Glu, Asp. GABA, Gln) concentrations. |
|
Formal Description Interaction-ID: 3203 |
drug/chemical compound increases_quantity of drug/chemical compound |
| Drugbank entries | Show/Hide entries for Pilocarpine |