CIDeRplusGeneral Information:
| Id: | 5,783 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
| Mammalia | |
| review | |
| Reference: | Rutter GA et al.(2015) Pancreatic beta-cell identity, glucose sensing and the control of insulin secretion Biochem. J. 466: 203-218 [PMID: 25697093] |
Interaction Information:
| Comment | Inhibitors of secretion include somatostatin, which acts in part via an inhibitory G protein, adrenaline (epinephrine) and noradrenaline (norepinephrine), the latter acting through alpha2 receptors to open KATP channels and hyperpolarize the cell. The actions of epinephrine (and norepinephrine) are important to suppress insulin release during exercise. |
|
Formal Description Interaction-ID: 54585 |
drug/chemical compound decreases_activity of process |