General Information:

Id: 548 (click here to show other Interactions for entry)
Diseases: Status epilepticus
Rattus norvegicus
Wistar
BTO:0000601 hippocampus
article
Reference: Khongsombat O et al.(2008) Acute effects of N-(2-propylpentanoyl)urea on hippocampal amino acid neurotransmitters in pilocarpine-induced seizure in rats Epilepsy Res. 79: 151-157 [PMID: 18439803]

Interaction Information:

Comment Pretreatment with either VPU (50 and 100 mg/kg) or VPA (300 and 600 mg/kg) completely abolished pilocarpine-evoked increases in extracellular glutamate and aspartate.
Formal Description
Interaction-ID: 5926

drug/chemical compound

Valproic acid

decreases_quantity of

drug/chemical compound

Asparagine

in pilocarpine model
Drugbank entries Show/Hide entries for Valproic acid