General Information:
Id: | 548 (click here to show other Interactions for entry) |
Diseases: |
Status epilepticus
|
Rattus norvegicus | |
Wistar | |
BTO:0000601 hippocampus | |
article | |
Reference: | Khongsombat O et al.(2008) Acute effects of N-(2-propylpentanoyl)urea on hippocampal amino acid neurotransmitters in pilocarpine-induced seizure in rats Epilepsy Res. 79: 151-157 [PMID: 18439803] |
Interaction Information:
Comment | Pretreatment with either N-(2-propylpentanoyl)urea (VPU) (50 and 100 mg/kg) or valproic acid (VPA) (300 and 600 mg/kg) completely abolished pilocarpine-evoked increases in extracellular glutamate and aspartate. |
Formal Description Interaction-ID: 2765 |
drug/chemical compound VPU decreases_quantity of drug/chemical compound |