General Information:

Id: 546 (click here to show other Interactions for entry)
Diseases: Status epilepticus
Rattus norvegicus
Wistar
BTO:0000601 hippocampus
article
Reference: Ermolinsky B et al.(2008) Differential changes in mGlu2 and mGlu3 gene expression following pilocarpine-induced status epilepticus: a comparative real-time PCR analysis. Brain Res. 1226: 173-180 [PMID: 18585369]

Interaction Information:

Comment Analysis of relative quantification (RQ) ratios of mGlu2 and mGlu3 mRNA expression revealed a significant down-regulation of both targets at 24 h after status epilepticus induced by pilocarpine.
Formal Description
Interaction-ID: 2762

drug/chemical compound

Pilocarpine

decreases_expression of

gene/protein

GRM2

in pilocarpine model
Drugbank entries Show/Hide entries for Pilocarpine or GRM2