General Information:

Id: 5,422 (click here to show other Interactions for entry)
Diseases: Metabolic
Mus musculus
article
Reference: Fox MA et al.(2013) Mutations in monoamine oxidase (MAO) genes in mice lead to hypersensitivity to serotonin-enhancing drugs: implications for drug side effects in humans Pharmacogenomics J. 13: 551-557 [PMID: 22964922]

Interaction Information:

Comment Compared with MAOA/B-WT mice, baseline tissue serotonin levels were increased about 2.6-3.9-fold in MAOA/B-KO mice. Following 5-HTP, serotonin levels were further increased about 4.5-6.2-fold in MAOA/B-KO mice.
Formal Description
Interaction-ID: 52903

gene/protein

MAOB

decreases_quantity of

drug/chemical compound

Serotonin

Drugbank entries Show/Hide entries for MAOB