Fox MA et al.(2013) Mutations in monoamine oxidase (MAO) genes in mice lead to hypersensitivity to serotonin-enhancing drugs: implications for drug side effects in humans Pharmacogenomics J. 13: 551-557
[PMID: 22964922]
Interaction Information:
Comment
Compared with MAOA/B-WT mice, baseline tissue serotonin levels were increased about 2.6-3.9-fold in MAOA/B-KO mice. Following 5-HTP, serotonin levels were further increased about 4.5-6.2-fold in MAOA/B-KO mice.
CIDeRplus