General Information:

Id: 5,421
Diseases: Metabolic
Neurological
Homo sapiens
article
Reference: Saito M et al.(2014) MAOA/B deletion syndrome in male siblings with severe developmental delay and sudden loss of muscle tonus Brain Dev. 36: 64-69 [PMID: 23414621]

Interaction Information:

Comment Deletion of the monoamine oxidase (MAO)-A and MAO-B was detected in two male siblings and in their mother. The serotonin levels in their cerebrospinal fluid were extremely elevated.
Formal Description
Interaction-ID: 52900

gene/protein

MAOB

decreases_quantity of

drug/chemical compound

Serotonin

in cerebrospinal fluid in two male siblings and in their mother ; experimentally shown via MAO-A and MAO-B deletion
Drugbank entries Show/Hide entries for MAOB
Comment Deletion of the monoamine oxidase (MAO)-A and MAO-B was detected in two male siblings and in their mother. The serotonin levels in their cerebrospinal fluid were extremely elevated.
Formal Description
Interaction-ID: 52901

gene/protein

MAOA

decreases_quantity of

drug/chemical compound

Serotonin

in cerebrospinal fluid in two male siblings and in their mother ; experimentally shown via MAO-A and MAO-B deletion
Drugbank entries Show/Hide entries for MAOA
Comment Deletion of the monoamine oxidase (MAO)-A and MAO-B was detected in two male siblings and in their mother. The serotonin levels in their cerebrospinal fluid were extremely elevated.
Formal Description
Interaction-ID: 102619

phenotype

decreased MAOB level

increases_quantity of

drug/chemical compound

Serotonin

in cerebrospinal fluid in two male siblings and in their mother
Comment Deletion of the monoamine oxidase (MAO)-A and MAO-B was detected in two male siblings and in their mother. The serotonin levels in their cerebrospinal fluid were extremely elevated.
Formal Description
Interaction-ID: 102620

phenotype

decreased MAOA level

increases_quantity of

drug/chemical compound

Serotonin

in cerebrospinal fluid in two male siblings and in their mother