CIDeRplusGeneral Information:
| Id: | 533 (click here to show other Interactions for entry) |
| Diseases: |
Alzheimer disease
- [OMIM]
Amyotrophic lateral sclerosis |
| Homo sapiens | |
| BTO:0000007 HEK-293 cell | |
| article | |
| Reference: | Rudrabhatla P et al.(2008) Pin1-dependent prolyl isomerization modulates the stress-induced phosphorylation of high molecular weight neurofilament protein J. Biol. Chem. 283 [PMID: 18635547] |
Interaction Information:
| Comment | Experimental motor neuron disease models are characterized by oxidative stress leading to the accumulation of phospho-NFs within perikarya. Treatment of transfected HEK293 cells with H(2)O(2) resulted in 6-fold increase of phosphorylated NF-H. |
|
Formal Description Interaction-ID: 2671 |
|