General Information:
Id: | 5,013 |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
Homo sapiens | |
article | |
Reference: | Millet L et al.(1998) Catecholamine effects on lipolysis and blood flow in human abdominal and femoral adipose tissue J. Appl. Physiol. 85: 181-188 [PMID: 9655773] |
Interaction Information:
Comment | Isoproterenol perfusion increased extracellular glycerol levels, but no differences were found by gender or fat-deposit site. |
Formal Description Interaction-ID: 49495 |
drug/chemical compound increases_quantity of drug/chemical compound |
Drugbank entries | Show/Hide entries for Isoproterenol or Glycerol |
Comment | Isoproterenol induced a greater increase in local blood flow in femoral adipose tissue than in abdominal adipose tissue in both genders. |
Formal Description Interaction-ID: 49497 |
drug/chemical compound increases_activity of phenotype increased blood flow |
Drugbank entries | Show/Hide entries for Isoproterenol |
Comment | Epinephrine and norepinephrine perfusion increased extracellular glycerol and reduced blood flow. No major differences were found according to gender and fat-deposit site. |
Formal Description Interaction-ID: 49499 |
drug/chemical compound increases_quantity of drug/chemical compound |
Drugbank entries | Show/Hide entries for |
Comment | Epinephrine and norepinephrine perfusion increased extracellular glycerol and reduced blood flow. No major differences were found according to gender and fat-deposit site. |
Formal Description Interaction-ID: 49500 |
drug/chemical compound increases_quantity of drug/chemical compound |
Drugbank entries | Show/Hide entries for |
Comment | Epinephrine and norepinephrine perfusion increased extracellular glycerol and reduced blood flow. No major differences were found according to gender and fat-deposit site. |
Formal Description Interaction-ID: 49501 |
drug/chemical compound increases_activity of phenotype decreased blood flow |
Comment | Epinephrine and norepinephrine perfusion increased extracellular glycerol and reduced blood flow. No major differences were found according to gender and fat-deposit site. |
Formal Description Interaction-ID: 49502 |
drug/chemical compound increases_activity of phenotype decreased blood flow |
Comment | As expected, change from supine to head-up posture (active tilt) induced a significant activation of the sympathetic nervous system (SNS), as assessed by the increase in plasma norepinephrine levels. Active tilt increased plasma glycerol, free fatty acid, norepinephrine levels, and extracellular glycerol concentration to the same extent whatever the gender and fat deposit. |
Formal Description Interaction-ID: 49504 |
tissue/cell line increases_quantity of drug/chemical compound |
Drugbank entries | Show/Hide entries for |
Comment | As expected, change from supine to head-up posture (active tilt) induced a significant activation of the sympathetic nervous system (SNS), as assessed by the increase in plasma norepinephrine levels. Active tilt increased plasma glycerol, free fatty acid, norepinephrine levels, and extracellular glycerol concentration to the same extent whatever the gender and fat deposit. |
Formal Description Interaction-ID: 49505 |
tissue/cell line increases_quantity of drug/chemical compound |
Comment | As expected, change from supine to head-up posture (active tilt) induced a significant activation of the sympathetic nervous system (SNS), as assessed by the increase in plasma norepinephrine levels. Active tilt increased plasma glycerol, free fatty acid, norepinephrine levels, and extracellular glycerol concentration to the same extent whatever the gender and fat deposit. |
Formal Description Interaction-ID: 49506 |
tissue/cell line increases_quantity of drug/chemical compound |