CIDeRplusGeneral Information:
| Id: | 4,769 (click here to show other Interactions for entry) |
| Diseases: |
Cardiovascular disease
|
| Canis lupus familiaris | |
| hypoperfused canine hearts | |
| article/cited | |
| Reference: | Fujita M et al.(2004) Selective blockade of serotonin 5-HT2A receptor increases coronary blood flow via augmented cardiac nitric oxide release through 5-HT1B receptor in hypoperfused canine hearts J. Mol. Cell. Cardiol. 37: 1219-1223 [PMID: 15572052] |
Interaction Information:
| Comment | Serotonin (5-HT) induces vasoconstriction via 5-HT2A receptors in smooth muscle cells and vasodilation through activating nitric oxide synthase eNOS via 5-HT1B receptors in endothelial cells. (cited information) |
|
Formal Description Interaction-ID: 47207 |
drug/chemical compound decreases_activity of process |