CIDeRplusGeneral Information:
| Id: | 46 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type I
- [OMIM]
|
| Rattus norvegicus | |
| BTO:0000991 pancreatic islet | |
| article | |
| Reference: | Manna P et al.(2009) Protective role of arjunolic acid in response to streptozotocin-induced type-I diabetes via the mitochondrial dependent and independent pathways. Toxicology 257: 53-63 [PMID: 19133311] |
Interaction Information:
| Comment | STZ (Streptozotocin) exposure caused increase in serum glucose level and established the condition of oxidative stress. |
|
Formal Description Interaction-ID: 122 |
|
| Drugbank entries | Show/Hide entries for Streptozocin |
| Comment | Arjunolic acid (AA) treatment both prior and post to the STZ exposure have found to be effective in inhibiting or reducing the STZ-induced pancreatic oxidative stress under hyperglycemic condition. |
|
Formal Description Interaction-ID: 134 |
drug/chemical compound Arjunolic acid decreases_activity of process |