CIDeRplusGeneral Information:
| Id: | 457 (click here to show other Interactions for entry) |
| Diseases: |
Alzheimer disease
- [OMIM]
|
| Mammalia | |
| review | |
| Reference: | de la Monte SM(2009) Insulin resistance and Alzheimers disease BMB Rep 42: 475-481 [PMID: 19712582] |
Interaction Information:
| Comment | GSK-3beta can be activated by oxidative stress, which is a consequence of insulin/IGF resistance and established feature of AD. |
|
Formal Description Interaction-ID: 2078 |
|
| Drugbank entries | Show/Hide entries for GSK3B |
| Comment | Induction of apoptosis is one of the possible responses to oxidative stress. |
|
Formal Description Interaction-ID: 36317 |
process increases_activity of |