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General Information:
Id:
4,465
Diseases:
Metabolic
Xenopus laevis
article
Reference:
Beyer T et al.(2012) Serotonin signaling is required for Wnt-dependent GRP specification and leftward flow in Xenopus Curr. Biol. 22: 33-39
[PMID: 22177902]
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Comment
Serotonin, which was found uniformly distributed along the main body axes in the early embryo, was required for Wnt signaling, which provides the instructive signal to specify the GRP. Importantly, serotonin was required for Wnt-induced double-axis formation as well.